Helicobacter pylori infection and antibiotic resistance — from biology to clinical implications

E Tshibangu-Kabamba, Y Yamaoka - Nature Reviews Gastroenterology …, 2021 - nature.com
Helicobacter pylori is a major human pathogen for which increasing antibiotic resistance
constitutes a serious threat to human health. Molecular mechanisms underlying this …

the global emergence of Helicobacter pylori antibiotic resistance

I Thung, H Aramin, V Vavinskaya… - Alimentary …, 2016 - Wiley Online Library
Background Helicobacter pylori is one of the most prevalent global pathogens and can lead
to gastrointestinal disease including peptic ulcers, gastric marginal zone lymphoma and …

[HTML][HTML] The emergence of antibiotic resistance by mutation

N Woodford, MJ Ellington - Clinical Microbiology and Infection, 2007 - Elsevier
The emergence of mutations in nucleic acids is one of the major factors underlying
evolution, providing the working material for natural selection. Most bacteria are haploid for …

Diagnosis of Helicobacter pylori: invasive and non-invasive tests

C Ricci, J Holton, D Vaira - Best Practice & Research Clinical …, 2007 - Elsevier
Helicobacter pylori infection can be diagnosed by invasive techniques requiring endoscopy
and biopsy (eg histological examination, culture and rapid urease test) and by non-invasive …

Clarithromycin-Resistant Genotypes and Eradication of Helicobacter pylori

V De Francesco, M Margiotta, A Zullo… - Annals of internal …, 2006 - acpjournals.org
Background: Three point mutations (A2143G, A2142G, and A2142C) have been involved in
Helicobacter pylori clarithromycin resistance. Objective: To compare the eradication rates …

Real-Time PCR Assay for Rapid and Accurate Detection of Point Mutations Conferring Resistance to Clarithromycin in Helicobacter pylori

M Oleastro, A Ménard, A Santos… - Journal of clinical …, 2003 - Am Soc Microbiol
The main cause of failure of Helicobacter pylori eradication therapy is resistance to
clarithromycin. The resistance is due to three point mutations in two positions on the 23S …

Helicobacter pylori and Antibiotic Resistance, A Continuing and Intractable Problem

Y Hu, M Zhang, B Lu, J Dai - Helicobacter, 2016 - Wiley Online Library
Helicobacter pylori, a human pathogen with a high global prevalence, is the causative
pathogen for multiple gastrointestinal diseases, especially chronic gastritis, peptic ulcers …

Diagnosis of Helicobacter pylori Using Invasive and Noninvasive Approaches

A Talebi Bezmin Abadi - Journal of pathogens, 2018 - Wiley Online Library
Helicobacter pylori (H. pylori) as gram‐negative and spiral microorganism is responsible for
colonization in the gastric microniche for more than 50% of world population. Recent studies …

Evaluation of a New Test, GenoType HelicoDR, for Molecular Detection of Antibiotic Resistance in Helicobacter pylori

E Cambau, V Allerheiligen, C Coulon… - Journal of Clinical …, 2009 - Am Soc Microbiol
The eradication rate of Helicobacter pylori by standard therapy is decreasing due to
antibiotic resistance, mainly to clarithromycin. Our aim was to provide a new molecular test …

Helicobacter pylori: pathology and diagnostic strategies

J Versalovic - American journal of clinical pathology, 2003 - academic.oup.com
Helicobacter pylori represents one of the most common and medically prominent infections
worldwide. Infection with this microaerobic, gram-negative bacterium has been established …