The present review article offers a detailed account of the design strategies employed for the
synthesis of nitrogen-containing anticancer agents. The results of different studies describe …

The practice of polypharmacology is not a new concept but the approaches which are being
adopted for administering the two or more drugs together are varied from time to time …

Benzimidazole, a fused heterocycle bearing benzene and imidazole has gained
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …

Background Cancer is a global health challenge, it impacts the quality of life and its
treatment is associated with several side effects. Resistance of the cancer cells to the …

Cancer is one of the leading causes of death worldwide. Mutation of the cell regulates genes
and protein causing cancer. Surgery, radiotherapy, and the use of anticancer agents are the …

Cancer is one of the major causes of worldwide human mortality. A wide range of cytotoxic
drugs are available on the market, and several compounds are in different phases of clinical …

In the last 2-3 decades, the broad research in the application of benzimidazole derivatives
made it important for mankind. Many scientists have worked on benzimidazole derivatives …

Cancer is one of the most serious medical problem and second leading cause of death in
the world, characterized by a deregulation of the cell cycle which mainly results in a …

Sixteen new thalidomide analogs were synthesized. The new candidates showed potent in
vitro antiproliferative activities against three human cancer cell lines, namely hepatocellular …

A series of heterocyclic compounds were synthesized and fully characterized. The geometry
optimization was carried out using the Density Functional Theory (DFT) method and the …