Estrogens have historically been associated with female reproduction, but work over the last
two decades established that estrogens and their main nuclear receptors (ESR1 and ESR2) …

After parturition, the uterus undergoes marked remodelling during involution; however, little
is known of the hormonal, cellular and molecular mechanisms that regulate this process …

Estrogen's presence in the male reproductive system has been known for over 60 years, but
its potential function in the epididymis remains an important area of investigation. Estrogen …

Estrogens play key roles in the development and maintenance of male reproductive function
and fertility. In this review, we briefly describe the localization and function of estrogen …

Novel Candidate Colorectal Cancer Biomarkers Identified by Methylation Microarray-Based
Scanning - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

A substantial advance in our understanding on the estrogen signaling occurred in the last
decade. Estrogens interact with two receptors, ESR1 and ESR2, also known as ERα and …

DNA hypermethylation is a common epigenetic abnormality in colorectal cancers (CRCs)
and a promising class of CRC screening biomarkers. We conducted a genome-wide search …

Seminiferous tubular atrophy may involve indirectly the disruption of estrogen receptor-α
(ESR1) function in efferent ductules of the testis. ESR1 helps to maintain fluid resorption by …

Follicle-stimulating hormone (FSH) stimulates the proliferation of immature Sertoli cells
through the activation of PI3K/AKT/mTORC1 and MEK/ERK1/2 pathways. Mature Sertoli …

Extracellular membrane vesicles (EVs) offer promising values in various medical fields, eg,
as biomarkers in liquid biopsies or as native (or bioengineered) biological nanocarriers in …