An enhanced isothermal amplification assay for viral detection

J Qian, SA Boswell, C Chidley, Z Lu, ME Pettit… - Nature …, 2020 - nature.com
Rapid, inexpensive, robust diagnostics are essential to control the spread of infectious
diseases. Current state of the art diagnostics are highly sensitive and specific, but slow, and …

Massively scaled-up testing for SARS-CoV-2 RNA via next-generation sequencing of pooled and barcoded nasal and saliva samples

JS Bloom, L Sathe, C Munugala, EM Jones… - Nature Biomedical …, 2021 - nature.com
Frequent and widespread testing of members of the population who are asymptomatic for
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential for the …

LAMP-Seq: population-scale COVID-19 diagnostics using combinatorial barcoding

JL Schmid-Burgk, RM Schmithausen, D Li, R Hollstein… - biorxiv, 2020 - biorxiv.org
The ongoing SARS-CoV-2 pandemic has already caused devastating losses. Exponential
spread can be slowed by social distancing and population-wide isolation measures, but …

LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding

KU Ludwig, RM Schmithausen, D Li, ML Jacobs… - Nature …, 2021 - nature.com
Frequent testing of large population groups combined with contact tracing and isolation
measures will be crucial for containing Coronavirus Disease 2019 outbreaks. Here we …

Swab-Seq: A high-throughput platform for massively scaled up SARS-CoV-2 testing

JS Bloom, L Sathe, C Munugala, EM Jones… - MedRxiv, 2021 - pmc.ncbi.nlm.nih.gov
The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is due
to the high rates of transmission by individuals who are asymptomatic at the time of …

Highly Flexible Deep-Learning-Based Automatic Analysis for Graphically Encoded Hydrogel Microparticles

JH Choi, W Jang, YJ Lim, SJ Mun, KW Bong - ACS sensors, 2023 - ACS Publications
Graphically encoded hydrogel microparticle (HMP)-based bioassay is a diagnostic tool
characterized by exceptional multiplex detectability and robust sensitivity and specificity …

Quantifying orthogonal barcodes for sequence census assays

AS Booeshaghi, KH Min, J Gehring… - Bioinformatics …, 2024 - academic.oup.com
Barcode-based sequence census assays utilize custom or random oligonucloetide
sequences to label various biological features, such as cell-surface proteins or CRISPR …

Efficient algorithms for the bee-identification problem

HM Kiah, A Vardy, H Yao - IEEE Journal on Selected Areas in …, 2023 - ieeexplore.ieee.org
The bee-identification problem, formally defined by Tandon, Tan, and Varshney (2019),
requires the receiver to identify “bees” using a set of unordered noisy measurements. In this …

Early sample tagging and pooling enables simultaneous SARS-CoV-2 detection and variant sequencing

A Chappleboim, D Joseph-Strauss, A Rahat… - Science Translational …, 2021 - science.org
Most severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic tests have
relied on RNA extraction followed by reverse transcription quantitative polymerase chain …

Bee identification problem for DNA strands

J Chrisnata, HM Kiah, A Vardy… - IEEE Journal on …, 2023 - ieeexplore.ieee.org
Motivated by DNA-based applications, we generalize the bee identification problem
proposed by Tandon et al.(2019). In this setup, we transmit all codewords from a codebook …