Promising therapeutic targets for treatment of rheumatoid arthritis

J Huang, X Fu, X Chen, Z Li, Y Huang… - Frontiers in …, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a systemic poly-articular chronic autoimmune joint disease that
mainly damages the hands and feet, which affects 0.5% to 1.0% of the population …

NF-kappaB signaling pathways in neurological inflammation: a mini review

RH Shih, CY Wang, CM Yang - Frontiers in molecular neuroscience, 2015 - frontiersin.org
The NF-κB (nuclear factor κ-light-chain-enhancer of activated B cells) transcription factor
family is a pleiotropic regulator of many cellular signaling pathways, providing a mechanism …

A zebrafish compound screen reveals modulation of neutrophil reverse migration as an anti-inflammatory mechanism

AL Robertson, GR Holmes, AN Bojarczuk… - Science translational …, 2014 - science.org
Diseases of failed inflammation resolution are common and largely incurable. Therapeutic
induction of inflammation resolution is an attractive strategy to bring about healing without …

Gene regulation of intracellular adhesion molecule-1 (ICAM-1): A molecule with multiple functions

M Singh, M Thakur, M Mishra, M Yadav, R Vibhuti… - Immunology letters, 2021 - Elsevier
Abstract Intracellular adhesion molecule 1 (ICAM-1) is one of the most extensively studied
inducible cell adhesion molecules which is responsible for several immune functions like T …

The NLRP3 inflammasome regulates adipose tissue metabolism

NG Barra, BD Henriksbo, FF Anhê… - Biochemical …, 2020 - portlandpress.com
Adipose tissue regulates metabolic homeostasis by participating in endocrine and immune
responses in addition to storing and releasing lipids from adipocytes. Obesity skews adipose …

Roles of intercellular cell adhesion molecule-1 (ICAM-1) in colorectal cancer: expression, functions, prognosis, tumorigenesis, polymorphisms and therapeutic …

Z Qiu, Y Wang, Z Zhang, R Qin, Y Peng, W Tang… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is a major global health problem and one of the major causes of
cancer-related death worldwide. It is very important to understand the pathogenesis of CRC …

[HTML][HTML] Intercellular adhesion molecule-1 suppresses TMZ chemosensitivity in acquired TMZ-resistant gliomas by increasing assembly of ABCB1 on the membrane

X Zhang, Y Tan, T Li, D Tan, B Fu, M Yang… - Drug Resistance …, 2024 - Elsevier
Aims Despite aggressive treatment, the recurrence of glioma is an inevitable occurrence,
leading to unsatisfactory clinical outcomes. A plausible explanation for this phenomenon is …

Sanguinaria canadensis: Traditional Medicine, Phytochemical Composition, Biological Activities and Current Uses

A Croaker, GJ King, JH Pyne… - International journal of …, 2016 - mdpi.com
Sanguinaria canadensis, also known as bloodroot, is a traditional medicine used by Native
Americans to treat a diverse range of clinical conditions. The plants rhizome contains …

The rich pharmacological activities of Magnolia officinalis and secondary effects based on significant intestinal contributions

L Niu, Y Hou, M Jiang, G Bai - Journal of Ethnopharmacology, 2021 - Elsevier
Abstract Ethnopharmacological relevance Magnolia officinalis Cortex (M. officinalis) is a
traditional herbal drug widely used in Asian countries. Depending on its multiple biological …

Pi-Dan-Jian-Qing decoction ameliorates type 2 diabetes mellitus through regulating the gut microbiota and serum metabolism

X Xie, J Liao, Y Ai, J Gao, J Zhao, F Qu, C Xu… - Frontiers in Cellular …, 2021 - frontiersin.org
Pi-Dan-Jian-Qing decoction (PDJQ) can been used in the treatment of type 2 diabetes
mellitus (T2DM) in clinic. However, the protective mechanisms of PDJQ on T2DM remain …