Nanopore technology and its applications in gene sequencing

B Lin, J Hui, H Mao - Biosensors, 2021 - mdpi.com
In recent years, nanopore technology has become increasingly important in the field of life
science and biomedical research. By embedding a nano-scale hole in a thin membrane and …

Glass capillary-based nanopores for single molecule/single cell detection

X Guan, H Li, L Chen, G Qi, Y Jin - ACS sensors, 2023 - ACS Publications
A glass capillary-based nanopore (G-nanopore), due to its tapered tip, easy tunability in
orifice size, and especially its flexible surface modifications that can be tailored to effectively …

Nanopore-based single-biomolecule interfaces: from information to knowledge

YL Ying, YT Long - Journal of the American Chemical Society, 2019 - ACS Publications
Single-molecule measurements have greatly enhanced our understanding of living systems.
Biological systems offer nanopores, a sub-class of membrane proteins, the well-defined …

Leveraging the power of long reads for targeted sequencing

SV Iyer, S Goodwin, WR McCombie - Genome Research, 2024 - genome.cshlp.org
Long-read sequencing technologies have improved the contiguity and, as a result, the
quality of genome assemblies by generating reads long enough to span and resolve …

Microfluidic-based nucleic acid amplification systems in microbiology

L Gorgannezhad, H Stratton, NT Nguyen - Micromachines, 2019 - mdpi.com
Rapid, sensitive, and selective bacterial detection is a hot topic, because the progress in this
research area has had a broad range of applications. Novel and innovative strategies for …

Nanopore detection of sub-nanosized plastics in PE-coated paper cups and analysis of their inflammatory responses

G Cho, K Kim, W Chen, S Son, TJ Jeon… - Chemical Engineering …, 2024 - Elsevier
In recent years, there has been growing global concern about environmental pollution, and
the increasing use of plastic products has made microplastics a serious environmental …

Metal nanoparticles and medicinal plants: Present status and future prospects in cancer therapy

S Jain, N Saxena, MK Sharma, S Chatterjee - Materials Today …, 2020 - Elsevier
Cancer is a deadly disease in which the abnormal cells divide in an uncontrolled manner. It
is the major cause of morbidity and mortality across the globe. To treat this disease, the …

Employing LiCl salt gradient in the wild-type α-hemolysin nanopore to slow down DNA translocation and detect methylated cytosine

T Vu, J Borgesi, J Soyring, M D'Alia, SL Davidson… - Nanoscale, 2019 - pubs.rsc.org
In this research, we demonstrate a label-free detection, biological nanopore-based method
to distinguish methylated cytosine (mC) from naked cytosine (C) in sample mixtures …

Epigenomics and gene regulation in mammalian social systems

TP Guerrero, J Fickel, S Benhaiem, A Weyrich - Current Zoology, 2020 - academic.oup.com
Social epigenomics is a new field of research that studies how the social environment
shapes the epigenome and how in turn the epigenome modulates behavior. We focus on …

Nanopore based detection of Bacillus thuringiensis HD-73 spores using aptamers and versatile DNA hairpins

J Park, MC Lim, H Ryu, J Shim, SM Kim, YR Kim… - Nanoscale, 2018 - pubs.rsc.org
A versatile nanopore sensing platform to detect any aptamer using nanopores by designing
DNA hairpins that are complementary to the aptamer is described. This platform can detect …