Endothelial dysfunction: the link between homocysteine and hydrogen sulfide

S Pushpakumar, S Kundu, U Sen - Current medicinal chemistry, 2014 - ingentaconnect.com
High level of homocysteine (hyperhomocysteinemia, HHcy) is associated with increased risk
for vascular disease. Evidence for this emerges from epidemiological studies which show …

The controversial role of HCY and vitamin B deficiency in cardiovascular diseases

W Herrmann, M Herrmann - Nutrients, 2022 - mdpi.com
Plasma homocysteine (HCY) is an established risk factor for cardiovascular disease CVD
and stroke. However, more than two decades of intensive research activities has failed to …

The chemistry of Alzheimer's disease

A Rauk - Chemical Society Reviews, 2009 - pubs.rsc.org
The chemistry of Alzheimer’s disease - Chemical Society Reviews (RSC Publishing) DOI:10.1039/B807980N
Royal Society of Chemistry View PDF VersionPrevious ArticleNext Article DOI: 10.1039/B807980N …

Structural organization of the neutrophil NADPH oxidase: phosphorylation and translocation during priming and activation

FR Sheppard, MR Kelher, EE Moore… - Journal of leukocyte …, 2005 - academic.oup.com
The reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is part of the
microbicidal arsenal used by human polymorphonuclear neutrophils (PMNs) to eradicate …

Hyperhomocysteinaemia and vascular injury: advances in mechanisms and drug targets

Y Fu, X Wang, W Kong - British journal of pharmacology, 2018 - Wiley Online Library
Homocysteine is a sulphur‐containing non‐proteinogenic amino acid.
Hyperhomocysteinaemia (HHcy), the pathogenic elevation of plasma homocysteine as a …

Coffee consumption and human health–beneficial or detrimental?–Mechanisms for effects of coffee consumption on different risk factors for cardiovascular disease …

T Ranheim, B Halvorsen - Molecular nutrition & food research, 2005 - Wiley Online Library
Coffee is probably the most frequently ingested beverage worldwide. Especially
Scandinavia has a high prevalence of coffee‐drinkers, and they traditionally make their …

Vascular oxidant stress and inflammation in hyperhomocysteinemia

L Papatheodorou, N Weiss - Antioxidants & redox signaling, 2007 - liebertpub.com
Elevated plasma levels of homocysteine are a metabolic risk factor for atherosclerotic
vascular disease, as shown in numerous clinical studies that linked elevated homocysteine …

Chemical pathology of homocysteine. IV. Excitotoxicity, oxidative stress, endothelial dysfunction, and inflammation

KS McCully - Annals of Clinical & Laboratory Science, 2009 - Assoc Clin Scientists
This review considers recent advances in the chemical pathology of homocysteine in
atherogenesis, oxidative metabolism, and carcinogenesis. Homocysteine is a potent …

MTHFR 677 C>T Polymorphism Reveals Functional Importance for 5-Methyltetrahydrofolate, Not Homocysteine, in Regulation of Vascular Redox State and …

C Antoniades, C Shirodaria, P Leeson, OA Baarholm… - Circulation, 2009 - Am Heart Assoc
Background—The role of circulating homocysteine as an atherosclerosis risk factor has
recently been questioned. However, 5-methyl-tetrahydrofolate (5-MTHF), the circulating …

Safe and effective antioxidant: the biological mechanism and potential pathways of ergothioneine in the skin

HM Liu, W Tang, XY Wang, JJ Jiang, W Zhang… - Molecules, 2023 - mdpi.com
Ergothioneine, a sulfur-containing micromolecular histidine derivative, has attracted
increasing attention from scholars since it was confirmed in the human body. In the human …