Small molecules in the treatment of COVID-19

S Lei, X Chen, J Wu, X Duan, K Men - Signal transduction and targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

Polymer incorporated magnetic nanoparticles: Applications for magnetoresponsive targeted drug delivery

F Sharifianjazi, M Irani, A Esmaeilkhanian… - Materials Science and …, 2021 - Elsevier
Efficient release and the delivery of active substances are necessary for diverse medical
applications including biosensors, biotechnology, and medical therapy. Meanwhile, drug …

Stem cell spheroids incorporating fibers coated with adenosine and polydopamine as a modular building blocks for bone tissue engineering

T Ahmad, H Byun, J Lee, SKM Perikamana, YM Shin… - Biomaterials, 2020 - Elsevier
Although stem cell spheroids offer great potential as functional building blocks for bottom-up
bone tissue engineering, delivery of bioactive signals remain challenging. Here, we …

[HTML][HTML] Gene therapy in epilepsy

L Zhang, Y Wang - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Gene therapy may constitute a promising alternative to conventional pharmacological tools
and surgeries for epilepsy. For primary epilepsy, a single variant leading to a significant …

The role of 3D printing in treating craniomaxillofacial congenital anomalies

CD Lopez, L Witek, A Torroni, RL Flores… - Birth defects …, 2018 - Wiley Online Library
Craniomaxillofacial congenital anomalies comprise approximately one third of all congenital
birth defects and include deformities such as alveolar clefts, craniosynostosis, and microtia …

RSM-CCD optimized in air synthesis of novel kappa-carrageenan/tamarind kernel powder hybrid polymer network incorporated with inclusion complex of (2 …

V Vaid, R Jindal - Journal of Drug Delivery Science and Technology, 2022 - Elsevier
The present research reported in air synthesis and optimization of the natural
polysaccharide-based hydrogel of kappa-carrageenan (KCG) and tamarind kernel powder …

Skin penetration enhancer-incorporated lipid nanovesicles (SPE-LNV) for skin brightening and wrinkle treatment

J Lee, M Noh, J Jang, JB Lee… - ACS Applied Materials …, 2022 - ACS Publications
In this work, we utilize skin penetration enhancers (SPEs) such as ceramide and fatty acids
in lipid nanovesicles to promote the transdermal delivery of active ingredients. These SPE …

In vivo sequestration of innate small molecules to promote bone healing

Y Zeng, YRV Shih, GS Baht, S Varghese - Advanced Materials, 2020 - Wiley Online Library
Approaches that enable innate repair mechanisms hold great potential for tissue repair.
Herein, biomaterial‐assisted sequestration of small molecules is described to localize pro …

Mild and large-scale synthesis of nanoscale metal-organic framework used as a potential adenine-based drug nanocarrier

TTT Nguyen, LHT Nguyen, NXD Mai, HKT Ta… - Journal of Drug Delivery …, 2021 - Elsevier
Nanoscale metal-organic frameworks (MOFs) have been a steady growing interest
worldwide in biomedical applications, especially in drug carriers. Adenosine, an unstable …

Recent advances on drug delivery nanocarriers for cerebral disorders

Z Zhou, T Sun, C Jiang - Biomedical Materials, 2021 - iopscience.iop.org
Pharmacotherapies for brain disorders are generally faced with obstacles from the blood-
brain barrier (BBB). There are a variety of drug delivery systems that have been put forward …