It has been established that 4.4 to 20% of the general population suffers from a major
depressive disorder (MDD), which is frequently associated with a dysregulation of normal …

This review explores the interface between circadian timekeeping and the regulation of
brain function by astrocytes. Although astrocytes regulate neuronal activity across many time …

The mammalian circadian system, which is comprised of multiple cellular clocks located in
the organs and tissues, orchestrates their regulation in a hierarchical manner throughout the …

Most physiology and behavior of mammalian organisms follow daily oscillations. These
rhythmic processes are governed by environmental cues (eg, fluctuations in light intensity …

Circadian cycles affect a variety of physiological processes, and disruptions of normal
circadian biology therefore have the potential to influence a range of disease-related …

Circadian rhythms are∼ 24-h oscillations in behavior and physiology, which are internally
generated and function to anticipate the environmental changes associated with the solar …

Plant fibers in byproduct streams produced by non-harsh food processing methods
represent biorepositories of diverse, naturally occurring, and physiologically active …

Sleep and circadian rhythm disruption are frequently observed in patients with psychiatric
disorders and neurodegenerative disease. The abnormal sleep that is experienced by these …

Sleep disturbance is increasingly recognized as an important, but understudied, mechanism
in the complex and multi-factorial causation of the symptoms and functional disability …

Mice deficient in the circadian transcription factor BMAL1 (brain and muscle ARNT-like
protein) have impaired circadian behavior and demonstrate loss of rhythmicity in the …