The vascular endothelial growth factor (VEGF)/vascular endothelial growth factor receptor
(VEGFR) axis is indispensable in the process of angiogenesis and has been implicated as a …

Prostate cancer progression is connected to the activity of conventional oncogenes and
tumour suppressors and driven by circulating steroid hormones. A key issue has been how …

Cohesin, a trimeric complex that establishes sister chromatid cohesion, has additional roles
in chromatin organization and transcription. We report that among those roles is the …

Understanding the cell biological mechanisms that enable tumor cells to persist after therapy
is necessary to improve the treatment of recurrent disease. Here, we demonstrate that …

Cancer is a multifaceted disease that involves several molecular mechanisms including
changes in gene expression. Two important processes altered in cancer that lead to …

This review comprehensively investigates the intricate interplay between small non-coding
RNAs (sncRNAs) and pancreatic ductal adenocarcinoma (PDAC), a devastating malignancy …

A shared characteristic of many tumors is the lack of response to anticancer drugs. Multiple
mechanisms of pharmacoresistance (MPRs) are involved in permitting cancer cells to …

Aberrant splicing is typically attributed to splice‐factor (SF) mutation and contributes to
malignancies including acute myeloid leukemia (AML). Here, we discovered a mutation …

All human genes undergo alternative splicing leading to the diversity of the proteins.
However, in some cases, abnormal regulation of alternative splicing can result in diseases …

Abnormal gene alternative splicing (AS) events are strongly associated with cancer
progression. Here, we summarize AS events that contribute to the development of drug …