Comparison of preprint postings of randomized clinical trials on COVID-19 and corresponding published journal articles: a systematic review

AD Bai, Y Jiang, DL Nguyen, CKL Lo… - JAMA Network …, 2023 - jamanetwork.com
Importance Randomized clinical trials (RCTs) on COVID-19 are increasingly being posted
as preprints before publication in a scientific, peer-reviewed journal. Objective To assess …

An Update on SARS-CoV-2 Clinical Trial Results—What We Can Learn for the Next Pandemic

BY Arman, J Brun, ML Hill, N Zitzmann… - International Journal of …, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic has claimed over 7 million lives
worldwide, providing a stark reminder of the importance of pandemic preparedness. Due to …

Rapid and validated UHPLC method for simultaneous determination of sofosbuvir, ledipasvir and paracetamol as commonly repurposed drugs for COVID-19 …

S Gamal, GG Mohamed, SA Salih, MI Ezzeldin… - Future Journal of …, 2023 - Springer
Abstract Background Sofosbuvir/ledipasvir (SOF/LDV), a combination of antiviral drugs, has
been recently repurposed for COVID-19 management, according to Food and Drug …

[HTML][HTML] Current status of therapeutic alternatives for COVID-19: A narrative review

AT Aslan, M Akova - Le infezioni in medicina, 2021 - ncbi.nlm.nih.gov
Since December 2019, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
infection has exploded and led to a global crisis. Currently, the global case numbers topped …

Even one dose of tocilizumab could hinder bad prognosis of cytokines storm in COVID-19 patients

MAS Elgohary, A Ali, SJ Alarfaj, H Shahin, AI Zaki… - Cytokine, 2024 - Elsevier
Severe COVID-19 pneumonia is a principal cause of death due to cascade of hyper
inflammatory condition that leading to lung damage. Therefore, an effective therapy to …

Clinical outcomes of sofosbuvir-based antivirals in patients with COVID-19: a systematic review and meta-analysis of randomized trials

CS Kow, A Javed, D Ramachandram… - Expert Review of Anti …, 2022 - Taylor & Francis
Background Several randomized trials have evaluated the effects of sofosbuvir-based direct-
acting antivirals on the clinical outcomes in patients with COVID-19. Methods A systematic …

Development and validation of a predictive scoring system for in-hospital mortality in COVID-19 egyptian patients: a retrospective study

MAS Elgohary, A Ali, TA El-Masry, H Faidah… - Scientific Reports, 2022 - nature.com
SARS-CoV-2 virus has rapidly spread worldwide since December 2019, causing COVID-19
disease. In-hospital mortality is a common indicator for evaluating treatment outcomes …

Current diagnostic and therapeutic approaches for severe acute respiratory syndrome coronavirus-2 (SARS-COV-2) and the role of nanomaterial-based theragnosis …

B Zhang, Q Wu, L Yin, J Zhang, W Gao… - Nanotechnology …, 2023 - degruyter.com
COVID-19 was the most devastating pandemic since the Spanish Flu of 1918, affecting 700
million individuals and causing 6.8 million fatalities globally. COVID-19 vaccines are …

Discovery of Bacterial Key Genes from 16S rRNA-Seq Profiles That Are Associated with the Complications of SARS-CoV-2 Infections and Provide Therapeutic …

MK Kibria, MA Ali, M Yaseen, IA Khan, MA Bhat… - Pharmaceuticals, 2024 - mdpi.com
SARS-CoV-2 infections, commonly referred to as COVID-19, remain a critical risk to both
human life and global economies. Particularly, COVID-19 patients with weak immunity may …

A Comprehensive Molecular and Clinical Investigation of Approved Anti-HCV Drugs Repurposing against SARS-CoV-2 Infection: A Glaring Gap between Benchside …

S Bansode, PK Singh, M Tellis, A Chugh, N Deshmukh… - Vaccines, 2023 - mdpi.com
The limited availability of effective treatment against SARS-CoV-2 infection is a major
challenge in managing COVID-19. This scenario has augmented the need for repurposing …