Introduction: Treatment of pediatric epilepsy requires a careful evaluation of the safety and
tolerability profile of antiepileptic drugs (AEDs) to avoid or minimize as much as possible …

Objective: Although vigabatrin (VGB) is effective and well tolerated for the treatment of
epileptic spasms, there are safety concerns. The aim of this systematic review and …

Congenital stationary night blindness (CSNB) is a heterogeneous group of non-progressive
inherited retinal disorders with characteristic electroretinogram (ERG) abnormalities. Riggs …

Recognising a potential visual-field (VF) defect in paediatric patients might be challenging,
especially in children before the age of 5 years and those with developmental delay or …

Purpose: Vigabatrin (VGB) is an effective antiepileptic that increases concentrations of
inhibitory γ-aminobutyric acid (GABA) by inhibiting GABA transaminase. Reports of VGB …

Purpose The antiepileptic drug vigabatrin is known to cause permanent loss of vision. Both
visual field testing and electroretinogram are used to detect retinal damage. Adult data on …

Aim To investigate the prevalence of vigabatrin‐attributed visual field defect (VAVFD) in
infantile spasms and the utility of optical coherence tomography (OCT) in detecting …

The co‐occurrence of hearing impairment and visual dysfunction is devastating. Most deaf‐
blind etiologies are genetically determined, the commonest being Usher syndrome (USH) …

Summary Vigabatrin (γ‐vinyl‐GABA) was developed as a structural γ‐aminobutyricacid
(GABA) analogue with a vinyl appendage through a systematic search for agents that can …

Purpose To evaluate the effects of the antiepileptic medication vigabatrin (VGB) on the retina
of pigmented rats. Methods Scotopic and photopic electroretinograms were recorded from …