Mathematical models for cell migration with real-time cell cycle dynamics

ST Vittadello, SW McCue, G Gunasingh, NK Haass… - Biophysical …, 2018 - cell.com
The fluorescent ubiquitination-based cell cycle indicator, also known as FUCCI, allows the
visualization of the G1 and S/G2/M cell cycle phases of individual cells. FUCCI consists of …

Travelling-wave analysis of a model of tumour invasion with degenerate, cross-dependent diffusion

C Colson, F Sánchez-Garduño… - … of the Royal …, 2021 - royalsocietypublishing.org
In this paper, we carry out a travelling-wave analysis of a model of tumour invasion with
degenerate, cross-dependent diffusion. We consider two types of invasive fronts of tumour …

A sharp-front moving boundary model for malignant invasion

M El-Hachem, SW McCue, MJ Simpson - Physica D: Nonlinear Phenomena, 2020 - Elsevier
We analyse a novel mathematical model of malignant invasion which takes the form of a two-
phase moving boundary problem describing the invasion of a population of malignant cells …

Travelling wave analysis of cellular invasion into surrounding tissues

M El-Hachem, SW McCue, MJ Simpson - Physica D: Nonlinear Phenomena, 2021 - Elsevier
Single-species reaction–diffusion equations, such as the Fisher–KPP and Porous-Fisher
equations, support travelling wave solutions that are often interpreted as simple …

Stability analysis of traveling wave fronts in a model for tumor growth

B Swartwood - Nonlinear Analysis: Real World Applications, 2025 - Elsevier
In this paper, we study the orbital stability of traveling wave solutions to the Gallay and
Mascia (GM) reduction of the Gatenby–Gawlinski model. The heteroclinic solutions provided …

Propagation fronts in a simplified model of tumor growth with degenerate cross-dependent self-diffusivity

T Gallay, C Mascia - Nonlinear Analysis: Real World Applications, 2022 - Elsevier
Motivated by tumor growth in Cancer Biology, we provide a complete analysis of existence
and non-existence of invasive fronts for the reduced Gatenby–Gawlinski model∂ t U= U f …

Traveling wave solutions in a model for tumor invasion with the acid-mediation hypothesis

PN Davis, P van Heijster, R Marangell… - Journal of Dynamics and …, 2022 - Springer
In this manuscript, we prove the existence of slow and fast traveling wave solutions in the
original Gatenby–Gawlinski model. We prove the existence of a slow traveling wave solution …

Numerical investigation of the Gatenby-Gawlinski model for acid-mediated tumour invasion

P Moschetta, C Simeoni - Rendiconti di Matematica e delle sue …, 2019 - hal.science
The Gatenby-Gawlinski model for the description of cancer invasion is taken into account
with the aim of investigating its structural aspects. From a phenomenological point of view …

Deformations of acid-mediated invasive tumors in a model with Allee effect

P Carter, A Doelman, P van Heijster, D Levy… - arXiv preprint arXiv …, 2024 - arxiv.org
We consider a Gatenby--Gawlinski-type model of invasive tumors in the presence of an
Allee effect. We describe the construction of bistable one-dimensional traveling fronts using …

Computational solution of an acid-mediated tumor-growth radial model under logistic growth regimes for normal and cancer cells

F Khan, M Abbas, JE Macías-Díaz… - International Journal …, 2023 - World Scientific
Tumor invasion follows a complex mechanism which involves cell migration and
proliferation. To study the processes in which primary and secondary metastases invade …