Evolving roles of lysyl oxidase family in tumorigenesis and cancer therapy

M Ye, Y Song, S Pan, M Chu, ZW Wang… - Pharmacology & …, 2020 - Elsevier
The lysyl oxidase (LOX) family is comprised of LOX and four LOX-like proteins (LOXL1,
LOXL2, LOXL3, and LOXL4), and mainly functions in the remodeling of extracellular matrix …

Anti-cancer potential of phytochemicals: the regulation of the epithelial-mesenchymal transition

S Liu, L Li, D Ren - Molecules, 2023 - mdpi.com
A biological process called epithelial-mesenchymal transition (EMT) allows epithelial cells to
change into mesenchymal cells and acquire some cancer stem cell properties. EMT …

Lysyl oxidase–like protein LOXL2 promotes lung metastasis of breast cancer

F Salvador, A Martin, C López-Menéndez… - Cancer research, 2017 - AACR
The lysyl oxidase–like protein LOXL2 has been suggested to contribute to tumor
progression and metastasis, but in vivo evidence has been lacking. Here we provide …

[HTML][HTML] USP5 promotes epithelial-mesenchymal transition by stabilizing SLUG in hepatocellular carcinoma

J Meng, X Ai, Y Lei, W Zhong, B Qian, K Qiao… - Theranostics, 2019 - ncbi.nlm.nih.gov
Rationale: The role of SLUG in epithelial-mesenchymal transition during tumor progression
has been thoroughly studied, but its precise regulation remains poorly explored. Methods …

COVID-19. Pandemic surgery guidance

BLDM Brücher, G Nigri, A Tinelli, J Florencio… - 4 OPEN, 2020 - iris.uniroma1.it
Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …

Honokiol inhibits breast cancer cell metastasis by blocking EMT through modulation of Snail/Slug protein translation

W Wang, Y Shang, Y Li, S Chen - Acta Pharmacologica Sinica, 2019 - nature.com
Honokiol (HNK), an active compound isolated from traditional Chinese medicine Magnolia
officinalis, has shown potent anticancer activities. In the present study, we investigated the …

Baicalein inhibits breast cancer growth via activating a novel isoform of the long noncoding RNA PAX8‐AS1‐N

X Yu, Y Cao, L Tang, Y Yang, F Chen… - Journal of cellular …, 2018 - Wiley Online Library
Baicalein, a natural flavonoid, has fascinating anti‐cancer properties in breast cancer. Long
noncoding RNAs (lncRNAs), a class of transcripts with no protein‐coding potential, also …

Baicalein suppresses non small cell lung cancer cell proliferation, invasion and Notch signaling pathway

G Su, H Chen, X Sun - Cancer Biomarkers, 2018 - content.iospress.com
BACKGROUND: Baicalein is an important Chinese herbal medicine and has multiple
pharmacological activities. However, the biological mechanisms of the anti-tumor effects of …

Complementary and alternative medicine and breast cancer

R Subramani, R Lakshmanaswamy - Progress in molecular biology and …, 2017 - Elsevier
Complementary and alternative medicine (CAM) has been in use among cancer patients for
a long time. There are several types of CAM that are practiced in various parts of the world …

Controlling metastatic cancer: the role of phytochemicals in cell signaling

A Kapinova, P Kubatka, A Liskova… - Journal of Cancer …, 2019 - Springer
Purpose Cancer is a serious health issue and a leading cause of death worldwide. Most of
the cancer patients (approximately 90%) do not die from the consequences of the primary …