Background Growing evidence suggests that epigenetic modification is vital in biological
processes of depression. Findings from studies exploring the associations between DNA …

Objective With its high prevalence, depression's pathogenesis remains unclear. Recent
attention has turned to the interplay between depression and epigenetic modifications …

Background We aim to identify the molecular mechanisms for curcumin's anti-depressant
properties, including genes, transcription factors, and miRNAs. Methods The Comparative …

Purpose To evaluate the prevalence of abnormal vitamin B12, folate, total homocysteine
(tHcy), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), C-reactive protein (CRP) levels …

Abstract Background The FKBP5 and NR3C1 genes play an important role in stress
response, thus impacting mental health. Stress factor exposure in early life, such as …

The NR3C1 glucocorticoid receptor (GR) gene is a component of the stress response
system, which can be regulated by epigenetic mechanisms. NR3C1 methylation has been …

The risk of depression is influenced by both genetic and environmental factors. It has been
suggested that epigenetic mechanisms may mediate the risk of depression following …

Abstract Major Depressive Disorder (MDD) is a common condition with complex
psychological and biological background. While its aetiology is still unclear, chronic stress …

The protein levels in a diet are correlated with immunity but the long-term intake of excessive
protein can compromise various aspects of health. L-theanine regulates immunity and …

The aim of this study was to investigate socioeconomic stressors predictive of depressive
symptoms and possible epigenetic changes in the glucocorticoid receptor–NR3C1-1F–an …