COVID-19 vaccines, effectiveness, and immune responses

HI Abufares, L Oyoun Alsoud, MAY Alqudah… - International journal of …, 2022 - mdpi.com
The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), has captivated the globe's attention since its emergence in 2019. This highly …

Protein subunit vaccines: Promising frontiers against COVID-19

VP Chavda, ENHK Ghali, PC Balar… - Journal of Controlled …, 2024 - Elsevier
The emergence of COVID-19 has posed an unprecedented global health crisis, challenging
the healthcare systems worldwide. Amidst the rapid development of several vaccine …

A Phase 3, randomized, non-inferiority study of a heterologous booster dose of SARS CoV-2 recombinant spike protein vaccine in adults

PS Kulkarni, B Gunale, S Kohli, S Lalwani, S Tripathy… - Scientific reports, 2023 - nature.com
Due to waning immunity following primary immunization with COVID-19 vaccines, booster
doses may be required. The present study assessed a heterologous booster of SII-NVX …

NVX-CoV2373-induced T-and B-cellular immunity in immunosuppressed people with multiple sclerosis that failed to respond to mRNA and viral vector SARS-CoV-2 …

M Mueller-Enz, C Woopen… - Frontiers in …, 2023 - frontiersin.org
Importance Immunological response to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) vaccination is important, especially in people with multiple sclerosis (pwMS) …

[HTML][HTML] Immunogenicity and safety of SARS-CoV-2 recombinant protein subunit vaccine (IndoVac) adjuvanted with alum and CpG 1018 in Indonesian adults: A phase …

A Nurdin, YM Nency, M Maddeppungeng, R Sekartini… - Vaccine, 2024 - Elsevier
Abstract Background Bio Farma has developed a recombinant protein subunit vaccine
(IndoVac) that is indicated for active immunization in population of all ages. This article …

Safety and immunogenicity of SARS-CoV-2 recombinant spike protein vaccine in children and adolescents in India: A Phase 2-3 randomized clinical trial

B Gunale, D Kapse, S Kar, A Bavdekar, S Kohli… - JAMA …, 2023 - jamanetwork.com
Importance The recombinant COVID-19 vaccine NVX-CoV2373 has demonstrated efficacy
of approximately 90% in adults; however, its safety and efficacy in children is unknown …

A pseudovirus-based neutralization assay for SARS-COV-2 variants: A rapid, cost-effective, BSL-2–based high-throughput assay useful for vaccine immunogenicity …

Z Cai, R Kalkeri, M Zhu, S Cloney-Clark, B Haner… - Microorganisms, 2024 - mdpi.com
Neutralizing antibody responses from COVID-19 vaccines are pivotal in conferring
protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Effective …

SAFETY AND IMMUNOGENICITY OF A PHH-1V BOOSTER DOSE AFTER DIFFERENT PRIME VACCINATION SCHEMES AGAINST COVID-19: PHASE III CLINICAL …

S Natalini Martinez, R Ramos, J Navarro-Perez… - medRxiv, 2024 - medrxiv.org
In this phase III, open label, single arm, multicenter clinical study, we report safety,
tolerability and immunogenicity of PHH-1V as a booster dose in subjects primary vaccinated …

[HTML][HTML] Adverse events following immunization of ChAdOx1 nCoV-19 vaccine among healthcare workers of a medicine-teaching institution of North India

A Jha, P Kumar, SK Goel, AA Bharatwal… - Journal of Family …, 2024 - journals.lww.com
Objective: This study sought to assess the prevalence of adverse events following
immunization (AEFI) and factors associated with AEFI of the ChAdOx1 nCoV-19 vaccine …

A Phase 2/3 observer-blind, randomized, controlled study to determine the safety and immunogenicity of SARS-CoV-2 recombinant spike protein vaccine in Indian …

B Gunale, D Kapse, S Kar, A Bavdekar, S Kohli… - medRxiv, 2023 - medrxiv.org
Background A recombinant, adjuvanted COVID-19 vaccine, SII-NVX-CoV2373 was
manufactured in India and evaluated in Indian children and adolescents to assess safety …