Design of Experiments Grants Mechanistic Insights into the Synthesis of Spermine-Containing PBAE Copolymers
APE Kromer, F Sieber-Schäfer… - … Applied Materials & …, 2024 - ACS Publications
Successful therapeutic delivery of siRNA with polymeric nanoparticles seems to be a
promising but not vastly understood and complicated goal to achieve. Despite years of …
promising but not vastly understood and complicated goal to achieve. Despite years of …
TransMA: an explainable multi-modal deep learning model for predicting properties of ionizable lipid nanoparticles in mRNA delivery
K Wu, Z Wang, X Yang, Y Chen, Z Han… - arXiv preprint arXiv …, 2024 - arxiv.org
As the primary mRNA delivery vehicles, ionizable lipid nanoparticles (LNPs) exhibit
excellent safety, high transfection efficiency, and strong immune response induction …
excellent safety, high transfection efficiency, and strong immune response induction …