Constraining the metabolic genotype–phenotype relationship using a phylogeny of in silico methods

NE Lewis, H Nagarajan, BO Palsson - Nature Reviews Microbiology, 2012 - nature.com
Reconstructed microbial metabolic networks facilitate a mechanistic description of the
genotype–phenotype relationship through the deployment of constraint-based …

Towards continuous industrial bioprocessing with solventogenic and acetogenic clostridia: challenges, progress and perspectives

CA Vees, CS Neuendorf, S Pflügl - Journal of Industrial …, 2020 - academic.oup.com
The sustainable production of solvents from above ground carbon is highly desired. Several
clostridia naturally produce solvents and use a variety of renewable and waste-derived …

The ModelSEED Biochemistry Database for the integration of metabolic annotations and the reconstruction, comparison and analysis of metabolic models for plants …

SMD Seaver, F Liu, Q Zhang, J Jeffryes… - Nucleic acids …, 2021 - academic.oup.com
For over 10 years, ModelSEED has been a primary resource for the construction of draft
genome-scale metabolic models based on annotated microbial or plant genomes. Now …

BacArena: Individual-based metabolic modeling of heterogeneous microbes in complex communities

E Bauer, J Zimmermann, F Baldini… - PLoS computational …, 2017 - journals.plos.org
Recent advances focusing on the metabolic interactions within and between cellular
populations have emphasized the importance of microbial communities for human health …

Optimizing genome-scale network reconstructions

J Monk, J Nogales, BO Palsson - Nature biotechnology, 2014 - nature.com
Optimizing genome-scale network reconstructions | Nature Biotechnology Skip to main content
Thank you for visiting nature.com. You are using a browser version with limited support for …

Multiscale computational models of complex biological systems

J Walpole, JA Papin, SM Peirce - Annual review of biomedical …, 2013 - annualreviews.org
Integration of data across spatial, temporal, and functional scales is a primary focus of
biomedical engineering efforts. The advent of powerful computing platforms, coupled with …

Microbial synthesis of n-butanol, isobutanol, and other higher alcohols from diverse resources

EI Lan, JC Liao - Bioresource technology, 2013 - Elsevier
Microbial production of fuel and chemical feedstock is a promising approach to solving
energy and environmental problems. n-Butanol, isobutanol and other higher alcohols are of …

[HTML][HTML] Cashew apple bagasse as new feedstock for the hydrogen production using dark fermentation process

JS Silva, JS Mendes, JAC Correia, MVP Rocha… - Journal of …, 2018 - Elsevier
Cashew apple bagasse (CAB) has been studied as feedstock for the biohydrogen
production using Clostridium roseum and the dark fermentation process. Pretreatment with …

Characterizing acetogenic metabolism using a genome-scale metabolic reconstruction of Clostridium ljungdahlii

H Nagarajan, M Sahin, J Nogales, H Latif… - Microbial cell …, 2013 - Springer
Background The metabolic capabilities of acetogens to ferment a wide range of sugars, to
grow autotrophically on H 2/CO 2, and more importantly on synthesis gas (H 2/CO/CO 2) …

Arginine deiminase pathway provides ATP and boosts growth of the gas-fermenting acetogen Clostridium autoethanogenum

K Valgepea, KQ Loi, JB Behrendorff… - Metabolic …, 2017 - Elsevier
Acetogens are attractive organisms for the production of chemicals and fuels from
inexpensive and non-food feedstocks such as syngas (CO, CO 2 and H 2). Expanding their …