Levamisole in children with idiopathic nephrotic syndrome: clinical efficacy and pathophysiological aspects

AK Mühlig, JY Lee, MJ Kemper, A Kronbichler… - Journal of Clinical …, 2019 - mdpi.com
Steroid sensitive nephrotic syndrome is one of the most common pediatric glomerular
diseases. Unfortunately, it follows a relapsing and remitting course in the majority of cases …

Change of the course of steroid-dependent nephrotic syndrome after rituximab therapy

K Benz, J Dötsch, W Rascher, D Stachel - Pediatric Nephrology, 2004 - Springer
A 16-year-old patient with steroid-dependent nephrotic syndrome with more than 35
relapses developed severe relapsing idiopathic thrombocytopenic purpura (ITP). At the age …

Levamisole in steroid-sensitive nephrotic syndrome of childhood: the lost paradise?

JC Davin, MP Merkus - Pediatric Nephrology, 2005 - Springer
Among the different drugs used for sparing steroids in steroid-sensitive nephrotic syndrome
(SSNS) with frequent relapses and steroid dependency, levamisole is the least toxic and the …

Quality of life in children with severe forms of idiopathic nephrotic syndrome in stable remission—A cross‐sectional study

A Roussel, JD Delbet, L Micheland… - Acta …, 2019 - Wiley Online Library
Aim Severe forms of idiopathic nephrotic syndrome (INS) require immunosuppressive
therapy: oral treatment or intravenous therapy (rituximab, RTX). The main objective was to …

Long-term effects of levamisole treatment in childhood nephrotic syndrome

V Sümegi, I Haszon, B Iványi, C Bereczki, F Papp… - Pediatric …, 2004 - Springer
The effects of levamisole treatment on long-term outcome were evaluated in a retrospective
study of frequently-relapsing (FRNS, n= 15), steroid-dependent (SDNS, n= 13), and steroid …

Experience with levamisole in frequently relapsing, steroid-dependent nephrotic syndrome

K Al-Saran, K Mirza, G Al-Ghanam, M Abdelkarim - Pediatric Nephrology, 2006 - Springer
This was a controlled prospective study on the use of an immunomodulator drug,
levamisole, in the treatment of frequently relapsing, steroid-dependent (FR/SD) idiopathic …

Levamisole therapy in children with frequently relapsing and steroid-dependent nephrotic syndrome: a single-center experience

E Kuźma-Mroczkowska, P Skrzypczyk… - … European Journal of …, 2016 - termedia.pl
Results: The duration of nephrotic syndrome was 3.4±2.9 years, and the number of relapses
before levamisole treatment was 6.0±3.4. The dose of prednisone on initiation of levamisole …

Short-and long-term efficacy of levamisole as adjunctive therapy in childhood nephrotic syndrome

O Boyer, JK Moulder, L Grandin, MJG Somers - Pediatric Nephrology, 2008 - Springer
Many children with steroid-dependent nephrotic syndrome (NS) have significant sequelae
despite steroid-sparing therapies. Levamisole may reduce short-term relapse frequency …

Long-term results of two unconventional agents in steroid-dependent nephrotic children

AF Donia, HM Ammar, AEB El-Agroudy… - Pediatric …, 2005 - Springer
Children with steroid-dependent minimal change nephrotic syndrome are prone to serious
steroid side effects. Alternative therapies, such as oral cyclophosphamide, may also have …

Levamisole in steroid-sensitive nephrotic syndrome children with frequent relapses and/or steroid dependency: comparison of daily and every-other-day usage

LS Fu, CY Shien, CS Chi - Nephron Clinical Practice, 2004 - karger.com
Steroid dependency (SD) and frequent relapses (FR) are common with steroid-sensitive
nephrotic syndrome (SSNS). We assessed the effectiveness of daily levamisole in 36 …