Trypanosoma cruzi, the agent of Chagas disease (ChD), exhibits remarkable biological and
genetic diversity, along with eco-epidemiological complexity. In order to facilitate …

Chagas disease caused by the parasite Trypanosoma cruzi affects millions of people.
Although its first genome dates from 2005, its complexity hindered a complete assembly and …

The protozoan Trypanosoma cruzi almost invariably establishes life-long infections in
humans and other mammals, despite the development of potent host immune responses …

AlphaFold2 and RoseTTAfold represent a transformative advance for predicting protein
structure. They are able to make very high-quality predictions given a high-quality alignment …

Chagas disease, caused by the protozoan Trypanosoma cruzi, is a serious chronic parasitic
disease, currently treated with Nifurtimox (NFX) and Benznidazole (BZ). In addition to high …

Chagas disease is an important vector-borne neglected tropical disease that causes great
health and economic losses. The etiological agent, Trypanosoma cruzi, is a protozoan …

Chronic manifestations of Chagas disease present as disabling and life-threatening
conditions affecting mainly the cardiovascular and gastrointestinal systems. Although …

Chagas disease (CD), caused by the protozoan parasite Trypanosoma cruzi, is considered
a neglected tropical disease by the World Health Organization. Congenital transmission of …

Chagas disease was described by Carlos Chagas, who first identified the parasite
Trypanosoma cruzi from a 2-year-old girl called Berenice. Many T. cruzi sequencing projects …

Chagas' disease is caused by the protozoan Trypanosoma cruzi, described in the early 20th
century by the Brazilian physician Dr. Carlos Chagas. There was a great amount of research …