[HTML][HTML] Death at a funeral: activation of the dead enzyme, MLKL, to kill cells by necroptosis

KA Davies, PE Czabotar, JM Murphy - Current Opinion in Structural Biology, 2024 - Elsevier
Necroptosis is a lytic form of programmed cell death implicated in inflammatory pathologies,
leading to intense interest in the underlying mechanisms and therapeutic prospects. Here …

A two-center prospective cohort study of serum RIP-3 as a potential biomarker in relation to severity and prognosis after severe traumatic brain injury

S Zou, J Xu, W Yang, Z Chen, H Shan, J Liu, D Tian… - Neurosurgical …, 2024 - Springer
Abstract Receptor-interacting protein kinase-3 (RIP-3) is a key component for inducing
necroptosis following acute brain injury. Purpose of this study is to unveil whether serum RIP …

A prospective cohort study regarding usability of serum RIPK3 as a biomarker in relation to early hematoma growth and neurological outcomes after acute …

B Li, D Wu, W Song, W Jiang, W Li - Clinica Chimica Acta, 2024 - Elsevier
Objective The receptor-interacting protein kinase 3 (RIPK3) is a pivotal component for
triggering necroptosis. We intended to investigate predictive effects of serum RIPK3 levels …

[HTML][HTML] Cardiovascular Disease: Mitochondrial dynamics and mitophagy crosstalk mechanisms with novel programmed cell death and macrophage polarisation

D Liu, H Qin, Y Gao, M Sun, M Wang - Pharmacological Research, 2024 - Elsevier
Several cardiovascular illnesses are associated with aberrant activation of cellular
pyroptosis, ferroptosis, necroptosis, cuproptosis, disulfidptosis and macrophage polarisation …

Silibinin induces both apoptosis and necroptosis with potential anti-tumor efficacy in lung cancer

G Zhang, L Wang, L Zhao, F Yang, C Lu… - Anti-Cancer Agents …, 2024 - benthamdirect.com
Background The incidence of lung cancer is steadily on the rise, posing a growing threat to
human health. The search for therapeutic drugs from natural active substances and …

Cancer-Associated Programmed Cell Death Mechanisms: Extended with Biochemical Markers and Experimental Approaches

GF Sengul, F Secer-Celik, G Pisiren - 2024 - Springer
Cell death is a fundamental mechanism of life that is directly associated with organismal
growth, development, aging, and diseases and is highly studied life science topic from …

[HTML][HTML] 荔枝蒂蛀虫海藻糖酶基因克隆及生物信息学分析

姚琼, 梁展图, 段双刚, 董易之, 徐淑, 李文景 - 广东农业科学, 2024 - gdnykx.gdaas.cn
目的海藻糖酶(Trehalase, Tre) 是昆虫体内海藻糖代谢的关键酶, 通过专一性地将海藻糖分解为
葡萄糖, 在昆虫能量代谢和生长发育中发挥着重要的作用. 旨在克隆荔枝蒂蛀虫(Conopomorpha …