Synthetic genetic polymers capable of heredity and evolution
Genetic information storage and processing rely on just two polymers, DNA and RNA, yet
whether their role reflects evolutionary history or fundamental functional constraints is …
whether their role reflects evolutionary history or fundamental functional constraints is …
Exploring the chemistry of genetic information storage and propagation through polymerase engineering
G Houlihan, S Arangundy-Franklin… - Accounts of chemical …, 2017 - ACS Publications
Conspectus Nucleic acids are a distinct form of sequence-defined biopolymer. What sets
them apart from other biopolymers such as polypeptides or polysaccharides is their unique …
them apart from other biopolymers such as polypeptides or polysaccharides is their unique …
Polymerase capable of producing non-DNA nucleotide polymers
P Holliger, C Cozens, V Pinheiro - US Patent 9,914,914, 2018 - Google Patents
NYHBQMYGNKIUIF-VKJDSPIKSA-N NC (NC1= O)= Nc2c1nc [n] 2 [C@@ H](C1O) O [C@
H](CO) C1O Chemical compound NC (NC1= O)= Nc2c1nc [n] 2 [C@@ H](C1O) O [C …
H](CO) C1O Chemical compound NC (NC1= O)= Nc2c1nc [n] 2 [C@@ H](C1O) O [C …