Extracellular matrix structure

AD Theocharis, SS Skandalis, C Gialeli… - Advanced drug delivery …, 2016 - Elsevier
Extracellular matrix (ECM) is a non-cellular three-dimensional macromolecular network
composed of collagens, proteoglycans/glycosaminoglycans, elastin, fibronectin, laminins …

The emerging role of ABL kinases in solid tumors

J Wang, AM Pendergast - Trends in cancer, 2015 - cell.com
The Abelson (ABL) tyrosine kinases have been identified as drivers of leukemia in mice and
humans. Emerging data demonstrate a role for the ABL family kinases, ABL1 and ABL2, in …

Multiplex detection of protease activity with quantum dot nanosensors prepared by intein-mediated specific bioconjugation

Z Xia, Y Xing, MK So, AL Koh, R Sinclair… - Analytical …, 2008 - ACS Publications
We report here a protease sensing nanoplatform based on semiconductor nanocrystals or
quantum dots (QDs) and bioluminescence resonance energy transfer (QD-BRET) to detect …

Maximizing the therapeutic efficacy of imatinib mesylate–loaded niosomes on human colon adenocarcinoma using Box-Behnken design

MA Kassem, HS El-Sawy, FI Abd-Allah… - Journal of …, 2017 - Elsevier
This research purposed to formulate an optimized imatinib mesylate (IM)–loaded niosomes
to improve its chemotherapeutic efficacy. The influence of 3 formulation factors on niosomal …

Collagen kinase receptors as potential therapeutic targets in metastatic colon cancer

M Lafitte, A Sirvent, S Roche - Frontiers in oncology, 2020 - frontiersin.org
Colorectal cancer (CRC) is one of the leading causes of tumor-related death worldwide.
While surgery can cure patients with early stage CRC, the 5-year survival rate is only 10 …

[HTML][HTML] Effects of ginsenoside Rh2 on growth and migration of pancreatic cancer cells

XP Tang, GD Tang, CY Fang, ZH Liang… - World Journal of …, 2013 - ncbi.nlm.nih.gov
AIM: To investigate the effects of ginsenoside Rh2 on the human pancreatic cancer cell line
Bxpc-3. METHODS: The human pancreatic cancer cell line Bxpc-3 was cultured in vitro and …

Evaluation of the effects of the flavonoid apigenin on apoptotic pathway gene expression on the colon cancer cell line (HT29)

M Turktekin, E Konac, HI Onen, E Alp… - Journal of medicinal …, 2011 - liebertpub.com
Abstract Apigenin (4′, 5, 7-trihydroxyflavone) is one of the leading components supporting
targeted treatment options. We explored the cytotoxic and apoptotic effects of various doses …

Overexpression of piRNA pathway genes in epithelial ovarian cancer

SL Lim, C Ricciardelli, MK Oehler, IMD De Arao Tan… - PloS one, 2014 - journals.plos.org
The importance of the Piwi-interacting RNA (piRNA) pathway for germ cell maintenance,
genome integrity, DNA methylation and retrotransposon control raises possible roles of this …

Controlled release and anti-proliferative effect of imatinib mesylate loaded sporopollenin microcapsules extracted from pollens of Betula pendula

I Sargin, L Akyuz, M Kaya, G Tan, T Ceter… - International journal of …, 2017 - Elsevier
Sporopollenin is a promising material for drug encapsulation due to its excellent properties;
uniformity in size, non-toxicity, chemically and thermally resilient nature. Herein …

[HTML][HTML] Estradiol–estrogen receptor: A key interplay of the expression of syndecan-2 and metalloproteinase-9 in breast cancer cells

OC Kousidou, A Berdiaki, D Kletsas, A Zafiropoulos… - Molecular …, 2008 - Elsevier
Estrogens are related with the growth and development of target tissues and play a critical
role in breast cancer progression. The effects of estrogens are mediated by the estrogen …