Stroke remains the leading cause of long-term disability with limited options available to aid
in recovery. Significant effort has been made to try and minimize neuronal damage following …

Spinal cord injury (SCI) results not only in motor and sensory deficits but also in autonomic
dysfunctions. The disruption of connections between higher brain centers and the spinal …

Spinal cord injury (SCI) is a devastating event that results in significant physical disabilities
for affected individuals. Apart from local injury within the spinal cord, SCI patients develop a …

Chondroitin sulfate proteoglycans (CSPGs) are a major class of axon growth inhibitors that
are up-regulated after spinal cord injury (SCI) and contribute to regenerative failure …

Chondroitin sulfate proteoglycans (CSPGs) are inhibitory extracellular matrix molecules that
are upregulated after CNS injury. Degradation of CSPGs using the enzyme chondroitinase …

There are now numerous preclinical reports of various experimental treatments promoting
some functional recovery after spinal cord injury. Surprisingly, perhaps, the mechanisms that …

The afferent innervation of the urinary bladder consists primarily of small myelinated (Aδ)
and unmyelinated (C-fiber) axons that respond to chemical and mechanical stimuli …

Spinal cord injury (SCI) is one of the most debilitating injuries in the world. Complications
after SCI, such as respiratory issues, bowel/bladder incontinency, pressure ulcers …

Rats have been the primary model to study the process and underlying mechanisms of
recovery after spinal cord injury. Two weeks after a severe spinal cord contusion, rats can …

Aims To summarize the changes that occur in the properties of bladder afferent neurons
following spinal cord injury. Methods Literature review of anatomical, immunohistochemical …