Cracking open bacterial membrane vesicles

T Nagakubo, N Nomura, M Toyofuku - Frontiers in Microbiology, 2020 - frontiersin.org
Membrane vesicles (MVs) are nanoparticles composed of lipid membranes that are
produced by both Gram-negative and Gram-positive bacteria. MVs have been assigned …

Outer membrane lipid secretion and the innate immune response to gram-negative bacteria

NP Giordano, MB Cian, ZD Dalebroux - Infection and immunity, 2020 - Am Soc Microbiol
The outer membrane (OM) of Gram-negative bacteria is an asymmetric lipid bilayer that
consists of inner leaflet phospholipids and outer leaflet lipopolysaccharides (LPS). The …

Model architectures for bacterial membranes

AB Carey, A Ashenden, I Köper - Biophysical reviews, 2022 - Springer
The complex composition of bacterial membranes has a significant impact on the
understanding of pathogen function and their development towards antibiotic resistance. In …

Bacterial vesicles block viral replication in macrophages via TLR4-TRIF-axis

J Bierwagen, M Wiegand, K Laakmann… - Cell Communication and …, 2023 - Springer
Gram-negative bacteria naturally secrete nano-sized outer membrane vesicles (OMVs),
which are important mediators of communication and pathogenesis. OMV uptake by host …

A novel decoy strategy for polymyxin resistance in Acinetobacter baumannii

J Park, M Kim, B Shin, M Kang, J Yang, TK Lee, W Park - Elife, 2021 - elifesciences.org
Modification of the outer membrane charge by a polymyxin B (PMB)-induced PmrAB two-
component system appears to be a dominant phenomenon in PMB-resistant Acinetobacter …

Polymyxins Bind to the Cell Surface of Unculturable Acinetobacter baumannii and Cause Unique Dependent Resistance

Y Zhu, J Lu, ML Han, X Jiang, MAK Azad… - Advanced …, 2020 - Wiley Online Library
Multidrug‐resistant Acinetobacter baumannii is a top‐priority pathogen globally and
polymyxins are a last‐line therapy. Polymyxin dependence in A. baumannii (ie …

Lipidomics analysis of outer membrane vesicles and elucidation of the inositol phosphoceramide biosynthetic pathway in Bacteroides thetaiotaomicron

MG Sartorio, E Valguarnera, FF Hsu… - Microbiology …, 2022 - Am Soc Microbiol
Approximately one-third of the human colonic microbiome is formed by bacteria from the
genus Bacteroides. These bacteria produce a large amount of uniformly sized outer …

Murine norovirus interaction with Enterobacter cloacae leads to changes in membrane stability and packaging of lipid and metabolite vesicle content

CA Mosby, MJ Edelmann, MK Jones - Microbiology Spectrum, 2023 - Am Soc Microbiol
Outer membrane vesicles (OMVs) are a primary means of communication for Gram-negative
bacteria. The specific role of vesicle components in cellular communication and how …

Outer-Membrane Vesicles of Fusobacterium necrophorum: A Proteomic, Lipidomic, and Functional Characterization

PK Bista, D Pillai, SK Narayanan - Microorganisms, 2023 - mdpi.com
Outer-membrane vesicles (OMVs) are extruded nanostructures shed by Gram-negative
bacteria, containing periplasmic contents, and often including virulence factors with …

Colistin Treatment Affects Lipid Composition of Acinetobacter baumannii

Y Tao, S Acket, E Beaumont, H Galez, L Duma… - Antibiotics, 2021 - mdpi.com
Multidrug-resistant Acinetobacter baumannii (A. baumannii) causes severe and often fatal
healthcare-associated infections due partly to antibiotic resistance. There are no studies on …