[HTML][HTML] Role of serotonin receptor signaling in cancer cells and anti-tumor immunity

S Karmakar, G Lal - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Serotonin or 5-hydroxytryptamine (5-HT) is a neurotransmitter known to affect
emotion, behavior, and cognition, and its effects are mostly studied in neurological diseases …

Effects of bisphenol A on the proliferation, migration, and tumor growth of colon cancer cells: In vitro and in vivo evaluation with mechanistic insights related to ERK …

JH Jun, JE Oh, JK Shim, YL Kwak, JS Cho - Food and Chemical Toxicology, 2021 - Elsevier
Bisphenol A (BPA) is a well-known endocrine-disrupting chemical related to the
carcinogenesis of estrogen-responsive organs. Although human exposure to BPA mainly …

5‑HT serotonin receptors modulate mitogenic signaling and impact tumor cell viability

Y Ballou, A Rivas, A Belmont… - Molecular and …, 2018 - spandidos-publications.com
Symptoms of depression are present in over half of all cancer patients, and selective
serotonin reuptake inhibitor (SSRI) anti‑depressant medications are prescribed to nearly a …

[HTML][HTML] 5-HT receptor agonist Valerenic Acid enhances the innate immunity signal and suppresses glioblastoma cell growth and invasion

Q Lu, Y Ding, Y Li - International Journal of Biological Sciences, 2020 - ncbi.nlm.nih.gov
Glioblastoma multiform (GBM) continues to threaten people's lives due to the limited
therapeutic strategies. As a new drug, Valerenic Acid suppresses the progression of GBM …

MiR-1256 inhibits cell proliferation and cell cycle progression in papillary thyroid cancer by targeting 5-hydroxy tryptamine receptor 3A

C Wu, L Ma, H Wei, F Nie, J Ning, T Jiang - Human cell, 2020 - Springer
Aberrant expression of miR-1256 has been reported to be closely associated with the
development and progression of tumors, including colon cancer and lung cancer. However …

[HTML][HTML] Evaluation of serotonin receptors (5HTR2A and 5HTR3A) mRNA expression changes in tumor of breast cancer patients

Z Olfati, G Rigi, H Vaseghi, Z Zamanzadeh… - Medical Journal of the …, 2020 - ncbi.nlm.nih.gov
Background: Several studies have proven the pattern of neurotransmitters, especially
serotonin, in carcinogenesis and tumor development. Several studies have also shown that …

Serotonin 5-HT7 receptor is a biomarker poor prognostic factor and induces proliferation of triple-negative breast cancer cells through FOXM1

V Cınar, Z Hamurcu, A Guler, N Nurdinov, B Ozpolat - Breast Cancer, 2022 - Springer
Background Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer
and associated with poor prognosis and shorter survival due to significant genetic …

Tropisetron attenuates tumor growth and progression in an experimental model of mouse lung cancer

M Rashidi, A Bazi, MR Shiran, A Bagheri… - Journal of Cellular …, 2020 - Wiley Online Library
The antineoplastic effects of 5‐hydroxytryptamine (5‐HT) receptor antagonists have been
shown in previous studies. However, the exact underlying mechanisms mediating these …

Role of Serotonergic System in Regulating Brain Tumor-Associated Neuroinflammatory Responses

S Karmakar, G Lal - Neuroprotection: Method and Protocols, 2024 - Springer
Serotonin signaling regulates wide arrays of both neural and extra-neural functions.
Serotonin is also found to affect cancer progression directly as well as indirectly by …

[HTML][HTML] Association between antipsychotic agents and risk of lung cancer: a nested case‐control study

J Li, F Tang, S Si, F Xue - Cancer Communications, 2022 - ncbi.nlm.nih.gov
Dear Editor, Antipsychotics are a class of psychotropic medication primarily used for the
treatment of schizophrenia and a range of other psychotic disorders. They are antagonists of …