This paper reviews the rapid advances that have been made in one form of optical biological
imaging in the last decade, namely that of light sheet microscopy. Although the concept was …

Fluorescence‐based microscopy is among the most successful methods in biological
studies. It played a critical role in the visualization of subcellular structures and in the …

Implementation of long-term, high spatiotemporal resolution SOFI is strongly dependent on
the performance of fluorescence probes, especially with regards to three essential optical …

Advances in the development of small photoblinking semiconducting polymer dots (Pdots)
have attracted great interest for use in super-resolution microscopy. However, multicolor …

Super-resolution microscopy techniques have pushed-down the limits of resolution in optical
imaging by more than an order of magnitude. However, these methods often require long …

Nondestructive pathology based on three-dimensional (3D) optical microscopy holds
promise as a complement to traditional destructive hematoxylin and eosin (H&E) stained …

Systematic imaging can be broadly defined as the systematic identification and
characterization of biological processes at multiple scales and levels. In contrast to …

Light sheet fluorescence microscopy (LSFM) has emerged as a transformative imaging
technique in the study of drug delivery and embryonic development, offering high-resolution …

Despite recent improvements in microscopy, it is still difficult to apply super-resolution
microscopy for deep imaging due to the deterioration of light convergence properties in thick …

摘要生物医学研究的发展对光学显微成像的性能, 如空间分辨率, 成像速度, 多维度信息,
成像质量等提出了更高的要求. 光片荧光显微采用一个薄片光从侧面激发样品 …