Adenoviruses are large (~ 950 Å) and complex non-enveloped, dsDNA icosahedral viruses.
They have a pseudo-T= 25 triangulation number with at least 12 different proteins …

We present structures of three immature tick-borne encephalitis virus (TBEV) isolates. Our
atomic models of the major viral components, the E and prM proteins, indicate that the pr …

Bacterial transposons are pervasive mobile genetic elements that use distinct DNA-binding
proteins for horizontal transmission. For example, Escherichia coli Tn 7 homes to a specific …

Plastic waste management is a pressing ecological, social, and economic challenge. The
saliva of the lepidopteran Galleria mellonella larvae is capable of oxidizing and …

Highlights•Cryo-EM has solved the structure of various adenovirus capsids, but not of the
core.•AFM probes biomechanics and induces/monitors disassembly of individual …

Chronic hepatitis B virus (HBV) infection poses a major global health challenge with
massive morbidity and mortality. Despite a preventive vaccine, current treatments provide …

Flaviviruses such as Dengue (DENV) or Zika virus (ZIKV) assemble into an immature form
within the endoplasmatic reticulum (ER), and are then processed by furin protease in the …

Sf6 is a bacterial virus that infects the human pathogen Shigella flexneri. Here, we describe
the cryo–electron microscopy structure of the Sf6 tail machine before DNA ejection, which …

Type 2 diabetes is associated with insulin resistance, impaired pancreatic β-cell insulin
secretion, and nonalcoholic fatty liver disease. Tissue-specific SWELL1 ablation impairs …

Zika virus (ZIKV) is an emerging mosquito borne flavivirus and a major public health concern
causing severe disease. Due to the presence of a lipid membrane and structural …