Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …

Every day we are bombarded by stimuli that must be assessed for their potential for harm or
benefit. Once a stimulus is learned to predict harm, it can elicit fear responses. Such learning …

Mounting evidence implicates microRNAs (miRNAs) in the pathology of schizophrenia.
These small noncoding RNAs bind to mRNAs containing complementary sequences and …

Social interactions are critical for mammalian survival and evolution. Dysregulation of social
behavior often leads to psychopathologies such as social anxiety disorder, denoted by …

Learning and memory formation rely on the precise spatiotemporal regulation of gene
expression, such as microRNA (miRNA)-associated silencing, to fine-tune gene expression …

Anabolic-androgenic steroids (AASs) can be used to treat both hormonal diseases and other
pathologies characterized by muscle loss (aging, cancer, and AIDS). Even if the adverse …

Phenotypic variation is a fundamental prerequisite for cell and organism evolution by natural
selection. Whereas the role of stochastic gene expression in phenotypic diversity of …

Adverse influences during pregnancy are associated with a range of unfavorable outcomes
for the developing offspring. Maternal psychosocial stress, exposure to infections and …

Dementia is a progressive cognitive diminution impeding with normal daily activities that is
constantly on the increase. Currently, the estimated prevalence is 50 million affected people …

The highly conserved transcription factor LIM-only 3 (Lmo3) is involved in important
neurodevelopmental processes in several brain areas including the amygdala, a central hub …