Validation of a rapid and sensitive high-performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) assay for the simultaneous determination of …
L Else, V Watson, J Tjia, A Hughes, M Siccardi… - … of Chromatography B, 2010 - Elsevier
Clinical pharmacokinetic studies of antiretrovirals require accurate and precise
measurement of plasma drug concentrations. Here we describe a simple, fast and sensitive …
measurement of plasma drug concentrations. Here we describe a simple, fast and sensitive …
A LC–tandem MS assay for the simultaneous measurement of new antiretroviral agents: Raltegravir, maraviroc, darunavir, and etravirine
A Fayet, A Béguin, B Zanolari, S Cruchon… - … of Chromatography B, 2009 - Elsevier
Raltegravir (RAL), maraviroc (MVC), darunavir (DRV), and etravirine (ETV) are new
antiretroviral agents with significant potential for drug interactions. This work describes a …
antiretroviral agents with significant potential for drug interactions. This work describes a …
Saquinavir, the pioneer antiretroviral protease inhibitor
CJL la Porte - Expert opinion on drug metabolism & toxicology, 2009 - Taylor & Francis
Background: The treatment of HIV infection underwent a major change in 1995 when
saquinavir was the first protease inhibitor introduced into the market. This drug made the use …
saquinavir was the first protease inhibitor introduced into the market. This drug made the use …
HPLC–MS method for the quantification of nine anti-HIV drugs from dry plasma spot on glass filter and their long term stability in different conditions
A D'Avolio, M Simiele, M Siccardi, L Baietto… - … of pharmaceutical and …, 2010 - Elsevier
A bioanalytical method for the determination of most commonly prescribed protease
inhibitors (saquinavir, atazanavir, amprenavir, darunavir, lopinavir and ritonavir) and non …
inhibitors (saquinavir, atazanavir, amprenavir, darunavir, lopinavir and ritonavir) and non …
HPLC–MS method for the simultaneous quantification of the antileukemia drugs imatinib, dasatinib and nilotinib in human peripheral blood mononuclear cell (PBMC)
A D'Avolio, M Simiele, S De Francia, A Ariaudo… - … of pharmaceutical and …, 2012 - Elsevier
A new method using high performance liquid chromatography coupled with electrospray
mass spectrometry is described for the quantification of PBMC concentration of tyrosine …
mass spectrometry is described for the quantification of PBMC concentration of tyrosine …
Population pharmacokinetic modeling of the association between 63396C→ T pregnane X receptor polymorphism and unboosted atazanavir clearance
A Schipani, M Siccardi, A D'Avolio… - Antimicrobial agents …, 2010 - Am Soc Microbiol
Atazanavir (ATV) plasma concentrations are influenced by CYP3A4 and ABCB1, which are
regulated by the pregnane X receptor (PXR; NR1I2). PXR expression is correlated with …
regulated by the pregnane X receptor (PXR; NR1I2). PXR expression is correlated with …
UPLC–MS/MS method for the simultaneous quantification of three new antiretroviral drugs, dolutegravir, elvitegravir and rilpivirine, and other thirteen antiretroviral …
M Simiele, A Ariaudo, A De Nicolò, F Favata… - … of pharmaceutical and …, 2017 - Elsevier
Abstract Rilpivirine (RPV), dolutegravir (DTG) and elvitegravir (EVG) are the latest
antiretroviral drugs approved for treatment of HIV infection. Currently, poor information is …
antiretroviral drugs approved for treatment of HIV infection. Currently, poor information is …
Tuning HIV drug release from a nanogel-based in situ forming implant by changing nanogel size
AR Town, J Taylor, K Dawson… - Journal of materials …, 2019 - pubs.rsc.org
HIV is a global public health threat and requires life-long, daily oral dosing to effectively
treat. This pill burden often results in poor adherence to the medications. An injectable in situ …
treat. This pill burden often results in poor adherence to the medications. An injectable in situ …
Determination of HIV drugs in biological matrices: a review
A Checa, R Oliver, S Hernández-Cassou… - Analytica chimica acta, 2009 - Elsevier
The present paper reviews the recent advances on the determination of antiretroviral drugs
against the human immunodeficiency virus (HIV). Methods have been reviewed with special …
against the human immunodeficiency virus (HIV). Methods have been reviewed with special …
A HPLC–MS method for the simultaneous quantification of fourteen antiretroviral agents in peripheral blood mononuclear cell of HIV infected patients optimized using …
A D'Avolio, M Simiele, M Siccardi, L Baietto… - … of pharmaceutical and …, 2011 - Elsevier
A sensitive and accurate high performance liquid chromatography–mass spectrometric
(HPLC–MS) method for the intracellular determination of 14 antiretroviral drugs in peripheral …
(HPLC–MS) method for the intracellular determination of 14 antiretroviral drugs in peripheral …