Understanding and engineering glycine cleavage system and related metabolic pathways for C1-based biosynthesis

J Ren, W Wang, J Nie, W Yuan, AP Zeng - One-carbon feedstocks for …, 2022 - Springer
The glycine cleavage system (GCS) is a fundamental component of life, widely existing in
microbes, plants, animals, and humans. A better understanding of the functionality and …

Structural analysis of merkel cell polyomavirus (MCPyV) viral capsid protein 1 (VP1) in HIV-1 infected individuals

C Prezioso, M Bianchi, F Obregon, M Ciotti… - International Journal of …, 2020 - mdpi.com
Merkel cell polyomavirus (MCPyV) viral protein 1 (VP1) is the capsid protein that mediates
virus attachment to host cell receptors and is the major immune target. Given the limited data …

A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites

JN Dienemann, SY Chen… - Angewandte Chemie …, 2023 - Wiley Online Library
The development of novel anti‐infectives requires unprecedented strategies targeting
pathways which are solely present in pathogens but absent in humans. Following this …

Eine chemisch‐proteomische Strategie identifiziert Inhibitoren der Lipoat‐Wiederverwertung in Bakterien und Parasiten

JN Dienemann, SY Chen, M Hitzenberger… - Angewandte …, 2023 - Wiley Online Library
Abstract Die Entwicklung neuer Antiinfektiva erfordert innovative Strategien zur gezielten
Ausnutzung von Stoffwechselwegen in Krankheitserregern, die in menschlichen Zellen …