Since our review of central 5-HT receptors and their function twenty years ago, no new 5-HT
receptor has been discovered and there is little evidence that this situation will change in the …

Agonist-activated G protein-coupled receptors (GPCRs) must correctly select from hundreds
of potential downstream signaling cascades and effectors. To accomplish this, GPCRs first …

Chronic pain has a high prevalence and a profound impact on patients and society, and its
treatment is a real challenge in clinical practice. Ginger is emerging as a promising …

gingerol, the representative single ingredient in ginger, was demonstrated antiemetic
properties against CINV via blocking the 5-hydroxytryptamine 3 receptors (5-HT 3 Rs) …

Ketamine is noted for its rapid onset antidepressant response and effectiveness in patients
with treatment resistant depression. While most research has focused on glutamatergic …

Over time, several studies have been conducted to demonstrate the functions of the
neurotransmitter 5-hydroxytryptamine (5-HT), better known as serotonin. This …

Abstract Background and Aim Hepatocellular carcinoma (HCC) is a malignant disease
worldwide. It is implicated in high cancer‐related mortality rates in humans. β‐Arrestin1 …

includes five articles aiming at characterizing the molecular mechanisms underlying HVD.
Serotonin or 5-hydroxytryptamine (5-HT) is a multifaceted neurotransmitter that regulates …

Neural stem cells (NSCs) have the ability to proliferate and differentiate into neurons,
astrocytes, oligodendrocytes and some other types of cells, which were used in therapies for …

Both the orexin peptides produced from prepro-orexin in orexinergic neurons of the lateral
hypothalamus and hypothalamic perifornical area (PFA) and serotonin coming to these …