Anatomic and physiologic age changes in the kidney

RD Lindeman, R Goldman - Experimental gerontology, 1986 - Elsevier
Cross-sectional studies of renal function in man indicate there is a progressive decline with
age after the age of 40 years. The blood vessels, glomeruli, tubules and interstitium are all …

Carcinogenesis and aging

VN Anisimov - Advances in cancer research, 1983 - Elsevier
Publisher Summary This chapter discusses the effect of aging on the sensitivity of some
tissues to chemical carcinogens. It also discusses the mechanism of carcinogenesis. This …

Decreased Enterobacteriaceae translocation due to gut microbiota remodeling mediates the alleviation of premature aging by a high‐fat diet

K Xu, Y Guo, Y Wang, Y Ren, V Low, S Cho, L Ping… - Aging …, 2023 - Wiley Online Library
Aging‐associated microbial dysbiosis exacerbates various disorders and dysfunctions, and
is a major contributor to morbidity and mortality in the elderly, but the underlying cause of …

Carcinogenesis and aging

VN Anisimov, NN Petrov - 1987 - osti.gov
This 2-voluem set discusses the problem of inter-relation between carcinogenesis and
aging, and the phenomenon of age-related increase in cancer incidence in animals and …

Elevated proliferation of proximal tubule cells and localization of accumulated α2u-globulin in F344 rats during chronic exposure to unleaded gasoline or 2, 2, 4 …

BG Short, VL Burnett, JA Swenberg - Toxicology and applied pharmacology, 1989 - Elsevier
In order to better characterize the pathogenesis of α2u-globulin (α2uG) nephropathy, cell
proliferation was quantitated within the three proximal tubule segments of the kidney (P1 …

Age changes of chromatin. A review

ZA Medvedev - Mechanisms of Ageing and Development, 1984 - Elsevier
The age-related studies of chromatin and DNA has attracted significant interest in recent
years. However, individual works describe only some and a few of the many changes of …

A system approach modelling of the three-stage non-linear kinetics in biological ageing

GU Crevecoeur - Mechanisms of ageing and development, 2001 - Elsevier
There is a widely observed non-linear kinetics in the ageing of biological systems, which is
characterised by three successive stages,(1) the ageing rate is firstly high, but decreases …

A new molecular model of cellular aging based on Werner syndrome

R Agrelo - Medical hypotheses, 2007 - Elsevier
In the Hayflick model, a decrease in the number of cells capable of undergoing proliferation
constitutes the main criterion of cellular aging and is closely linked to organismal aging …

Replication of total and mitochondrial DNA in rat liver with aging

AY Litoshenko, EL Levitsky - Experimental Gerontology, 1981 - Elsevier
Replication of total (t-DNA) and mitochondrial (mt-DNA) liver DNA of adult (6 months) and
old (24 months) female rats labelled with iv 3 H-thymidine has beeb studied. The most part …

[图书][B] Quantitative general adaptation

GU Crevecoeur - 2008 - researchgate.net
The first time I heard about logarithms, it was at school-as for many people, I guess.
However, I remember this event as if it occurred yesterday because the teacher in our school …