Functional magnetic resonance imaging methods

JE Chen, GH Glover - Neuropsychology review, 2015 - Springer
Since its inception in 1992, Functional Magnetic Resonance Imaging (fMRI) has become an
indispensible tool for studying cognition in both the healthy and dysfunctional brain. FMRI …

Multiple testing corrections, nonparametric methods, and random field theory

TE Nichols - Neuroimage, 2012 - Elsevier
I provide a selective review of the literature on the multiple testing problem in fMRI. By
drawing connections with the older modalities, PET in particular, and how software …

Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer's disease

B Bellaver, G Povala, PCL Ferreira, JP Ferrari-Souza… - Nature medicine, 2023 - nature.com
An unresolved question for the understanding of Alzheimer's disease (AD) pathophysiology
is why a significant percentage of amyloid-β (Aβ)-positive cognitively unimpaired (CU) …

Small sample sizes reduce the replicability of task-based fMRI studies

BO Turner, EJ Paul, MB Miller, AK Barbey - Communications biology, 2018 - nature.com
Despite a growing body of research suggesting that task-based functional magnetic
resonance imaging (fMRI) studies often suffer from a lack of statistical power due to too …

Association of cannabis use during adolescence with neurodevelopment

MD Albaugh, J Ottino-Gonzalez, A Sidwell… - JAMA …, 2021 - jamanetwork.com
Importance Animal studies have shown that the adolescent brain is sensitive to disruptions
in endocannabinoid signaling, resulting in altered neurodevelopment and lasting behavioral …

Vector field statistical analysis of kinematic and force trajectories

TC Pataky, MA Robinson, J Vanrenterghem - Journal of biomechanics, 2013 - Elsevier
When investigating the dynamics of three-dimensional multi-body biomechanical systems it
is often difficult to derive spatiotemporally directed predictions regarding experimentally …

Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: relationship to neuroimaging and CSF biomarkers

K Nho, A Kueider-Paisley… - Alzheimer's & …, 2019 - Elsevier
Abstract Introduction Bile acids (BAs) are the end products of cholesterol metabolism
produced by human and gut microbiome co-metabolism. Recent evidence suggests gut …

Association of altered liver enzymes with Alzheimer disease diagnosis, cognition, neuroimaging measures, and cerebrospinal fluid biomarkers

K Nho, A Kueider-Paisley, S Ahmad… - JAMA network …, 2019 - jamanetwork.com
Importance Increasing evidence suggests an important role of liver function in the
pathophysiology of Alzheimer disease (AD). The liver is a major metabolic hub; therefore …

Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease

NJ Ashton, AL Benedet, TA Pascoal, TK Karikari… - …, 2022 - thelancet.com
Background Phosphorylated tau (p-tau) epitopes in cerebrospinal fluid (CSF) are accurate
biomarkers for a pathological and clinical diagnosis of Alzheimer's disease (AD) and are …

Tensor regression with applications in neuroimaging data analysis

H Zhou, L Li, H Zhu - Journal of the American Statistical Association, 2013 - Taylor & Francis
Classical regression methods treat covariates as a vector and estimate a corresponding
vector of regression coefficients. Modern applications in medical imaging generate …