microRNAs biogenesis, functions and role in tumor angiogenesis

T Annese, R Tamma, M De Giorgis, D Ribatti - Frontiers in oncology, 2020 - frontiersin.org
microRNAs (miRNAs) are small non-coding RNA molecules, evolutionary conserved. They
target more than one mRNAs, thus influencing multiple molecular pathways, but also …

MicroRNAs and complex diseases: from experimental results to computational models

X Chen, D Xie, Q Zhao, ZH You - Briefings in bioinformatics, 2019 - academic.oup.com
Plenty of microRNAs (miRNAs) were discovered at a rapid pace in plants, green algae,
viruses and animals. As one of the most important components in the cell, miRNAs play a …

miRNA targets: from prediction tools to experimental validation

G Riolo, S Cantara, C Marzocchi, C Ricci - Methods and protocols, 2020 - mdpi.com
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression in both animals
and plants. By pairing to microRNA responsive elements (mREs) on target mRNAs, miRNAs …

[HTML][HTML] Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis

SA Melo, H Sugimoto, JT O'Connell, N Kato… - Cancer cell, 2014 - cell.com
Exosomes are secreted by all cell types and contain proteins and nucleic acids. Here, we
report that breast cancer associated exosomes contain microRNAs (miRNAs) associated …

microRNA-382 as a tumor suppressor? Roles in tumorigenesis and clinical significance

M Fattahi, S Shahrabi, F Saadatpour, D Rezaee… - International journal of …, 2023 - Elsevier
MicroRNAs (miRNAs) are small single-stranded RNAs belonging to a class of non-coding
RNAs with an average length of 18–22 nucleotides. Although not able to encode any …

MicroRNA profiling: approaches and considerations

CC Pritchard, HH Cheng, M Tewari - Nature Reviews Genetics, 2012 - nature.com
MicroRNAs (miRNAs) are small RNAs that post-transcriptionally regulate the expression of
thousands of genes in a broad range of organisms in both normal physiological contexts …

MicroRNA signatures in human cancers

GA Calin, CM Croce - Nature reviews cancer, 2006 - nature.com
MicroRNA (miRNA) alterations are involved in the initiation and progression of human
cancer. The causes of the widespread differential expression of miRNA genes in malignant …

Micro-RNA: The darkhorse of cancer

M Budakoti, AS Panwar, D Molpa, RK Singh… - Cellular signalling, 2021 - Elsevier
The discovery of micro RNAs (miRNA) in cancer has opened up new vistas for researchers
in recent years. Micro RNAs area set of small, endogenous, highly conserved, non-coding …

Real-time quantification of microRNAs by stem–loop RT–PCR

C Chen, DA Ridzon, AJ Broomer, Z Zhou… - Nucleic acids …, 2005 - academic.oup.com
A novel microRNA (miRNA) quantification method has been developed using stem–loop RT
followed by TaqMan PCR analysis. Stem–loop RT primers are better than conventional ones …

[HTML][HTML] microRNAs as oncogenes and tumor suppressors

B Zhang, X Pan, GP Cobb, TA Anderson - Developmental biology, 2007 - Elsevier
microRNAs (miRNAs) are a new class of non-protein-coding, endogenous, small RNAs.
They are important regulatory molecules in animals and plants. miRNA regulates gene …