Therapeutic potential of phenolic compounds in medicinal plants—Natural health products for human health

W Sun, MH Shahrajabian - Molecules, 2023 - mdpi.com
Phenolic compounds and flavonoids are potential substitutes for bioactive agents in
pharmaceutical and medicinal sections to promote human health and prevent and cure …

The Golden Spice for Life: Turmeric with the Pharmacological Benefits of Curcuminoids Components, Including Curcumin, Bisdemethoxycurcumin, and …

MH Shahrajabian, W Sun - Current organic synthesis, 2024 - ingentaconnect.com
Background: Turmeric (Curcuma longa L.), belonging to the Zingiberaceae family, is a
perennial rhizomatous plant of tropical and subtropical regions. The three major chemical …

Natural compounds as promising adjuvant agents in the treatment of gliomas

F Persano, G Gigli, S Leporatti - International Journal of Molecular …, 2022 - mdpi.com
In humans, glioblastoma is the most prevalent primary malignant brain tumor. Usually,
glioblastoma has specific characteristics, such as aggressive cell proliferation and rapid …

Therapeutic potentials of curcumin in the treatment of glioblstoma

Z Shabaninejad, MH Pourhanifeh… - European journal of …, 2020 - Elsevier
Glioblastoma multiforme (GBM), a greatly aggressive malignancy of the brain, is correlated
with a poor prognosis and low rate of survival. Up to now, chemotherapy and radiation …

Crosstalk between PI3K/AKT/mTOR and WNT/β-Catenin signaling in GBM-Could combination therapy checkmate the collusion?

SD Precilla, I Biswas, SS Kuduvalli, TS Anitha - Cellular Signalling, 2022 - Elsevier
Glioblastoma multiforme is one of the calamitous primary glial brain tumors with extensive
heterogeneity at cellular and molecular levels. While maximal surgical resection trailed by …

The multi-faceted effect of curcumin in glioblastoma from rescuing cell clearance to autophagy-independent effects

L Ryskalin, F Biagioni, CL Busceti, G Lazzeri, A Frati… - Molecules, 2020 - mdpi.com
The present review focuses on the multi-faceted effects of curcumin on the neurobiology
glioblastoma multiforme (GBM), with a special emphasis on autophagy (ATG)-dependent …

Natural products as promising targets in glioblastoma multiforme: a focus on NF-κB signaling pathway

M Soukhtanloo, E Mohtashami, A Maghrouni… - Pharmacological …, 2020 - Springer
Background Glioblastoma multiforme (GBM), as the broadest cerebrum tumor, is resistant to
current medical interventions, particularly chemo/radiation. Hence, it necessitates further …

Demethoxycurcumin induces apoptosis in HER2 overexpressing bladder cancer cells through degradation of HER2 and inhibiting the PI3K/Akt pathway

CC Kao, YC Cheng, MH Yang, TL Cha… - Environmental …, 2021 - Wiley Online Library
Bladder cancer is the most common malignancy of the urinary tract and arising from the
epithelial lining of the urinary bladder. Resistance to cytotoxic therapies is associated with …

Natural small molecules targeting NF-κB signaling in glioblastoma

MS Uddin, MT Kabir, AA Mamun, MS Sarwar… - Frontiers in …, 2021 - frontiersin.org
Nuclear factor-κB (NF-κB) is a transcription factor that regulates various genes that mediate
various cellular activities, including propagation, differentiation, motility, and survival …

Harmaline exerts potentially anti-cancer effects on U-87 human malignant glioblastoma cells in vitro

MM Vahedi, A Shahini, M Mottahedi, S Garousi… - Molecular Biology …, 2023 - Springer
Background Harmaline is a β-carboline alkaloid that can be extracted from the seeds of
Peganum harmala. Harmaline has been shown to exhibit a potent cytotoxic effect against …