Synthetic polypeptides: from polymer design to supramolecular assembly and biomedical application

Z Song, Z Han, S Lv, C Chen, L Chen, L Yin… - Chemical Society …, 2017 - pubs.rsc.org
Synthetic polypeptides from the ring-opening polymerization of N-carboxyanhydrides
(NCAs) are one of the most important biomaterials. The unique features of these synthetic …

Synthesis of side-chain modified polypeptides

TJ Deming - Chemical reviews, 2016 - ACS Publications
Proteins have long fascinated scientists since their complex sequences and diversity of
chemical functionality can lead to structurally defined folded chains with highly specific …

Functional polypeptide and hybrid materials: Precision synthesis via α-amino acid N-carboxyanhydride polymerization and emerging biomedical applications

C Deng, J Wu, R Cheng, F Meng, HA Klok… - Progress in Polymer …, 2014 - Elsevier
Polypeptides derived from naturally occurring α-amino acids have emerged as a unique and
versatile family of bio-inspired biomaterials that can be tailor-made for varying biomedical …

Stimuli responsive synthetic polypeptides derived from N-carboxyanhydride (NCA) polymerisation

J Huang, A Heise - Chemical Society Reviews, 2013 - pubs.rsc.org
The progress in NCA polymerisation combined with advanced orthogonal functionalization
techniques as well as the integration with other controlled polymerisation techniques …

Recent advances in amino acid N-carboxyanhydrides and synthetic polypeptides: chemistry, self-assembly and biological applications

H Lu, J Wang, Z Song, L Yin, Y Zhang… - Chemical …, 2014 - pubs.rsc.org
Polypeptides are fascinating materials with unique properties for various biological
materials. We highlight here recent advances in amino acid N-carboxyanhydrides (NCAs) …

Stimuli‐sensitive synthetic polypeptide‐based materials for drug and gene delivery

C He, X Zhuang, Z Tang, H Tian… - Advanced healthcare …, 2012 - Wiley Online Library
Stimuli‐sensitive synthetic polypeptides are unique biodegradable and biocompatible
synthetic polymers with structures mimicking natural proteins. These polymers exhibit …

Amino acid-derived stimuli-responsive polymers and their applications

K Bauri, M Nandi, P De - Polymer Chemistry, 2018 - pubs.rsc.org
Natural biopolymers such as proteins and nucleic acids in living organisms possess an
inherent ability to respond to local environmental stimuli, which motivated researchers to …

Recent Advances and Future Perspectives of Synthetic Polypeptides from N-Carboxyanhydrides

Z Song, Z Tan, J Cheng - Macromolecules, 2019 - ACS Publications
Synthetic polypeptides, the analogues of natural proteins, are important biomaterials that
have found broad biomedical applications. Ring-opening polymerization of N …

Thermoresponsive Polypeptides from Pegylated Poly-l-glutamates

C Chen, Z Wang, Z Li - Biomacromolecules, 2011 - ACS Publications
The synthesis and characterization of new thermoresponsive pegylated poly-l-glutamate
(poly-l-EG x Glu) are described. The obtained polypeptides display low critical solution …

Gold-catalyzed glycosylation in the synthesis of complex carbohydrate-containing natural products

W Li, B Yu - Chemical Society Reviews, 2018 - pubs.rsc.org
The methodological developments in gold (I)-and gold (III)-catalyzed glycosylation reactions
are fully surveyed, which exploit the special alkynophilicity or the Lewis acidity of the gold …