Applications of metals for bone regeneration

K Glenske, P Donkiewicz, A Köwitsch… - International journal of …, 2018 - mdpi.com
The regeneration of bone tissue is the main purpose of most therapies in dental medicine.
For bone regeneration, calcium phosphate (CaP)-based substitute materials based on …

[HTML][HTML] Degradation of 3D-printed magnesium phosphate ceramics in vitro and a prognosis on their bone regeneration potential

G Eugen, M Claus, S Anna-Maria, D Niklas, S Philipp… - Bioactive Materials, 2023 - Elsevier
Regenerative bone implants promote new bone formation and ideally degrade
simultaneously to osteogenesis. Although clinically established calcium phosphate bone …

Strontium substitution in apatitic CaP cements effectively attenuates osteoclastic resorption but does not inhibit osteoclastogenesis

M Schumacher, AS Wagner, J Kokesch-Himmelreich… - Acta biomaterialia, 2016 - Elsevier
Strontium ions were discovered to exert a dual effect on bone turnover, namely an inhibition
of cell-driven bone resorption and a simultaneous stimulation of new bone tissue formation …

[PDF][PDF] Relevance of osteoclast-specific enzyme activities in cell-based in vitro resorption assays

A Bernhardt, K Koperski, M Schumacher… - Eur Cell …, 2017 - researchgate.net
Cell-based in vitro resorption assays are an important tool to simulate the in vivo
biodegradation of resorbable bone graft materials and to predict their clinical performance …

[HTML][HTML] Visfatin alters the cytokine and matrix-degrading enzyme profile during osteogenic and adipogenic MSC differentiation

L Tsiklauri, J Werner, M Kampschulte… - Osteoarthritis and …, 2018 - Elsevier
Objectives Age-related bone loss is associated with bone marrow adiposity. Adipokines (eg,
visfatin, resistin, leptin) are adipocyte-derived factors with immunomodulatory properties and …

Biomimetic mineralizable collagen hydrogels for dynamic bone matrix formation to promote osteogenesis

L Chen, C Wu, S Chen, Y Zhang, A Liu… - Journal of materials …, 2020 - pubs.rsc.org
The simulation of the native bone matrix formation process is crucial for the construction of
the cellular microenvironment for bone regeneration. However, it is still challenging to …

Osteogenic differentiation capacity of human mesenchymal stromal cells in response to extracellular calcium with special regard to connexin 43

AS Wagner, K Glenske, V Wolf, D Fietz… - Annals of Anatomy …, 2017 - Elsevier
The effects of extracellular calcium on osteogenic differentiation capacity of human bone-
derived mesenchymal stromal cells with special regard to connexin 43 (cx43) have been …

Calcite incorporated in silica/collagen xerogels mediates calcium release and enhances osteoblast proliferation and differentiation

S Rößler, R Unbehau, T Gemming, B Kruppke… - Scientific Reports, 2020 - nature.com
Multiphasic silica/collagen xerogels are biomaterials designed for bone regeneration.
Biphasic silica/collagen xerogels (B30) and triphasic xerogels (B30H20 or B30CK20) …

Biomaterial based treatment of osteoclastic/osteoblastic cell imbalance–Gelatin-modified calcium/strontium phosphates

B Kruppke, AS Wagner, M Rohnke… - Materials Science and …, 2019 - Elsevier
Osteoporotic bone represents–particularly in case of fractures–difficult conditions for its
regeneration. In the present study, the focus was put on a degradable bone substitute …

Strontium ions promote in vitro human bone marrow stromal cell proliferation and differentiation in calcium‐lacking media

B Kruppke, C Heinemann, AS Wagner… - Development …, 2019 - Wiley Online Library
In order to investigate the influence of calcium and strontium ion concentration on human
bone marrow stromal cells and their differentiation to osteoblasts, different cell culture media …