An update on treatment options for pancreatic adenocarcinoma

A Lambert, L Schwarz, I Borbath… - … in medical oncology, 2019 - journals.sagepub.com
Pancreatic cancer is one of the most lethal solid organ tumors. Due to the rising incidence,
late diagnosis, and limited treatment options, it is expected to be the second leading cause …

Relationship between surgeon volume and outcomes: a systematic review of systematic reviews

J Morche, T Mathes, D Pieper - Systematic reviews, 2016 - Springer
Background The surgeon volume-outcome relationship has been discussed for many years
and its existence or nonexistence is of importance for various reasons. A lot of empirical …

Minimally invasive versus open distal pancreatectomy (LEOPARD): a multicenter patient-blinded randomized controlled trial

T de Rooij, J van Hilst, H van Santvoort… - Annals of …, 2019 - journals.lww.com
Objective: This trial followed a structured nationwide training program in minimally invasive
distal pancreatectomy (MIDP), according to the IDEAL framework for surgical innovation …

Toward a consensus on centralization in surgery

R Vonlanthen, P Lodge, JS Barkun, O Farges… - Annals of …, 2018 - journals.lww.com
Objectives: To critically assess centralization policies for highly specialized surgeries in
Europe and North America and propose recommendations. Background/Methods: Most …

Improvement of surgical results for pancreatic cancer

W Hartwig, J Werner, D Jäger, J Debus… - The Lancet …, 2013 - thelancet.com
Surgery is the only potential hope of cure for patients with pancreatic cancer. Advantageous
tumour characteristics and complete tumour resection are the factors most relevant for a …

Effect of hospital volume on surgical outcomes after pancreaticoduodenectomy: a systematic review and meta-analysis

T Hata, F Motoi, M Ishida, T Naitoh, Y Katayose… - Annals of …, 2016 - journals.lww.com
Objective: The aim of the study was to evaluate the relationship between hospital volume
and outcome after pancreaticoduodenectomy (PD). Summary Background Data: Previous …

Impact of nationwide centralization of pancreaticoduodenectomy on hospital mortality

Dutch Pancreatic Cancer Group de Wilde … - Journal of British …, 2012 - academic.oup.com
Background The impact of nationwide centralization of pancreaticoduodenectomy (PD) on
mortality is largely unknown. The aim of this study was to analyse changes in hospital …

Impact of centralization of pancreatic cancer surgery on resection rates and survival

GA Gooiker, V Lemmens, MG Besselink… - Journal of British …, 2014 - academic.oup.com
Background Centralization of pancreatic surgery has been shown to reduce postoperative
mortality. It is unknown whether resection rates and survival have also improved. The aim of …

Hospital volume and mortality for 25 types of inpatient treatment in German hospitals: observational study using complete national data from 2009 to 2014

U Nimptsch, T Mansky - BMJ open, 2017 - bmjopen.bmj.com
Objectives To explore the existence and strength of a relationship between hospital volume
and mortality, to estimate minimum volume thresholds and to assess the potential benefit of …

Advanced-stage pancreatic cancer: therapy options

J Werner, SE Combs, C Springfeld, W Hartwig… - Nature reviews Clinical …, 2013 - nature.com
Pancreatic ductal adenocarcinoma is one of the most aggressive cancers, and surgical
resection is a requirement for a potential cure. However, the majority of patients are …