The genetic factors associated with susceptibility or resistance to viral infections are likely to
involve a sophisticated array of immune response. These genetic elements may modulate …

Celiac disease (CD) is a complex immune-related disease with a very strong genetic
component. Multiple genetic findings over the last decade have added to the already known …

Summary β-Coronaviruses are a family of positive-strand enveloped RNA viruses that
includes the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much is …

Aims/hypothesis Human pancreatic beta cells may be complicit in their own demise in type 1
diabetes, but how this occurs remains unclear. One potentially contributing factor is …

Problem The extravillous trophoblasts (EVT) express HLA‐C and HLA‐G, but HLA‐E and
HLA‐F are the subject of conflicting reports. In this study, we define the HLA expression …

To monitor the health of cells, the immune system tasks antigen-presenting cells with
gathering antigens from other cells and bringing them to CD8 T cells in the form of peptides …

Abstract Killer Ig-like receptors (KIRs) are innate immune receptors expressed by NK and T
cells classically associated with the detection of missing self through loss of their respective …

Background Neoantigen (NeoAg) peptides displayed at the tumor cell surface by human
leukocyte antigen molecules show exquisite tumor specificity and can elicit T cell mediated …

BACKGROUND Although the immune system intuitively must have an important role in
embryo implantation and in the achievement of a pregnancy, the molecular details have for …

Based on previous findings supporting HLA-F as a ligand for KIR3DL2 and KIR2DS4, we
investigated the potential for MHC-I open conformers (OCs) as ligands for KIR3DS1 and …