Cellular senescence, a process in which a cell exits the cell cycle in response to stressors, is
one of the hallmarks of aging. Senescence and the senescence-associated secretory …

It is estimated that, at minimum, 500 million individuals suffer from cellular metabolic
dysfunction, such as diabetes mellitus (DM), throughout the world. Even more concerning is …

Chronic inflammation and hypoxia in the microenvironment of diabetic foot ulcers (DFUs)
can result in sustained vascular impairment, hindering tissue regeneration. While both nitric …

The intricate interplay between cellular senescence and alterations in the gut microbiome
emerges as a pivotal axis in the aging process, increasingly recognized for its contribution to …

Disorders of metabolism affect multiple systems throughout the body but may have the
greatest impact on both central and peripheral nervous systems. Currently available …

Life expectancy is increasing throughout the world and coincides with a rise in non-
communicable diseases (NCDs), especially for metabolic disease that includes diabetes …

As a significant non-communicable disease, cardiovascular disease is the leading cause of
death for both men and women, comprises almost twenty percent of deaths in most racial …

Cellular senescence is a biological mechanism that prevents abnormal cell proliferation
during tissue repair, and it is often accompanied by the secretion of various factors, such as …

Diabetic wounds (DWs) are a common complication of diabetes mellitus; DWs have a low
cure rate and likely recurrence, thus affecting the quality of patients' lives. As traditional …

Metabolic disorders and diabetes (DM) impact more than five hundred million individuals
throughout the world and are insidious in onset, chronic in nature, and yield significant …