Pathophysiology and immunolgical basis of axial spondyloarthritis
MGH van de Sande, D Elewaut - Best Practice & Research Clinical …, 2023 - Elsevier
Over the recent years the wider availability and application of state-of-the-art immunological
technologies greatly advanced the insight into the mechanisms that play an important role in …
technologies greatly advanced the insight into the mechanisms that play an important role in …
Exploring the Pathogenesis of Spondylarthritis beyond HLA-B27: A Descriptive Review
RE Nagit, E Rezus, P Cianga - International Journal of Molecular …, 2024 - mdpi.com
Spondylarthritis (SpA) is a chronic inflammatory condition that encompasses damage to the
axial or peripheral skeleton, accompanied by specific extra-articular symptoms. Within this …
axial or peripheral skeleton, accompanied by specific extra-articular symptoms. Within this …
CHOP-mediated IL-23 overexpression does not drive colitis in experimental spondyloarthritis
HLA-B27 is a major risk factor for spondyloarthritis (SpA), yet the underlying mechanisms
remain unclear. HLA-B27 misfolding-induced IL-23, which is mediated by endoplasmic …
remain unclear. HLA-B27 misfolding-induced IL-23, which is mediated by endoplasmic …
Biology of HLA class I associated inflammatory diseases
A Bordbar, O Manches, J Nowatzky - Best Practice & Research Clinical …, 2024 - Elsevier
Human leukocyte antigen (HLA) class I association is a well-established feature of common
and uncommon inflammatory diseases, but it is unknown whether it impacts the …
and uncommon inflammatory diseases, but it is unknown whether it impacts the …
HLA-B* 57: 01-dependent intracellular stress in keratinocytes triggers dermal hypersensitivity reactions to abacavir
A Kazaoka, S Fujimori, Y Yamada, T Shirayanagi… - PNAS …, 2024 - academic.oup.com
Specific human leukocyte antigen (HLA) polymorphisms combined with certain drug
administration strongly correlate with skin eruption. Abacavir hypersensitivity, which is …
administration strongly correlate with skin eruption. Abacavir hypersensitivity, which is …
ERAP1 and the return of the UPR in ankylosing spondylitis
N Haroon, RD Inman - Nature Reviews Rheumatology, 2023 - nature.com
The mechanisms underlying the genetic association between HLA-B27 and ankylosing
spondylitis, including the contribution of endoplasmic reticulum aminopeptidase 1 (ERAP1) …
spondylitis, including the contribution of endoplasmic reticulum aminopeptidase 1 (ERAP1) …
Polymorphic positions 349 and 725 of the autoimmunity-protective allotype 10 of ER aminopeptidase 1 are key in determining its unique enzymatic properties
G Georgaki, A Mpakali, M Trakada, A Papakyriakou… - bioRxiv, 2024 - biorxiv.org
ER aminopeptidase 1 (ERAP1) is a polymorphic intracellular aminopeptidase with key roles
in antigen presentation and adaptive immune responses. ERAP1 allotype 10 is highly …
in antigen presentation and adaptive immune responses. ERAP1 allotype 10 is highly …
Spondiloartritisi u sklopu upalnih bolesti crijeva
S Nižić - 2023 - repozitorij.mef.unizg.hr
Spondiloartritisi su heterogena grupa kroničnih upalnih mišićno-koštanih bolesti koje imaju
sličnosti u kliničkim, serološkim, radiološkim i imunogenetskim obilježjima. Grupa sadrži …
sličnosti u kliničkim, serološkim, radiološkim i imunogenetskim obilježjima. Grupa sadrži …