Developments in toxicogenomics: understanding and predicting compound-induced toxicity from gene expression data
B Alexander-Dann, LL Pruteanu, E Oerton… - Molecular omics, 2018 - pubs.rsc.org
The toxicogenomics field aims to understand and predict toxicity by using 'omics' data in
order to study systems-level responses to compound treatments. In recent years there has …
order to study systems-level responses to compound treatments. In recent years there has …
Lung models to evaluate silver nanoparticles' toxicity and their impact on human health
JG González-Vega, JC García-Ramos… - Nanomaterials, 2022 - mdpi.com
Nanomaterials (NMs) solve specific problems with remarkable results in several industrial
and scientific areas. Among NMs, silver nanoparticles (AgNPs) have been extensively …
and scientific areas. Among NMs, silver nanoparticles (AgNPs) have been extensively …
Bioinformatics and system biology approach to identify the influences of SARS-CoV-2 infections to idiopathic pulmonary fibrosis and chronic obstructive pulmonary …
SMH Mahmud, M Al-Mustanjid, F Akter… - Briefings in …, 2021 - academic.oup.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), better known as
COVID-19, has become a current threat to humanity. The second wave of the SARS-CoV-2 …
COVID-19, has become a current threat to humanity. The second wave of the SARS-CoV-2 …
Poisson representation: a bridge between discrete and continuous models of stochastic gene regulatory networks
Stochastic gene expression dynamics can be modelled either discretely or continuously.
Previous studies have shown that the mRNA or protein number distributions of some simple …
Previous studies have shown that the mRNA or protein number distributions of some simple …
Identification of common molecular signatures of SARS-CoV-2 infection and its influence on acute kidney injury and chronic kidney disease
W Zhang, L Liu, X Xiao, H Zhou, Z Peng… - Frontiers in …, 2023 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the main cause of
COVID-19, causing hundreds of millions of confirmed cases and more than 18.2 million …
COVID-19, causing hundreds of millions of confirmed cases and more than 18.2 million …
SoCube: an innovative end-to-end doublet detection algorithm for analyzing scRNA-seq data
Doublets formed during single-cell RNA sequencing (scRNA-seq) severely affect
downstream studies, such as differentially expressed gene analysis and cell trajectory …
downstream studies, such as differentially expressed gene analysis and cell trajectory …
Identification of the effects of COVID-19 on patients with pulmonary fibrosis and lung cancer: a bioinformatics analysis and literature review
Y Li, L Niu - Scientific reports, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) poses a serious threat to human health and
life. The effective prevention and treatment of COVID-19 complications have become crucial …
life. The effective prevention and treatment of COVID-19 complications have become crucial …
Transcriptomic responses of potato to drought stress
EB Aliche, T Gengler, I Hoendervangers, M Oortwijn… - Potato Research, 2022 - Springer
Transcriptomic changes in plants during drought stress give insights into the mechanisms
with which plants stabilise their metabolic processes in order to cope with the drought …
with which plants stabilise their metabolic processes in order to cope with the drought …
Exploration of the shared molecular mechanisms between COVID-19 and neurodegenerative diseases through Bioinformatic analysis
Y Shi, W Liu, Y Yang, Y Ci, L Shi - International Journal of Molecular …, 2023 - mdpi.com
The COVID-19 pandemic has caused millions of deaths and remains a major public health
burden worldwide. Previous studies found that a large number of COVID-19 patients and …
burden worldwide. Previous studies found that a large number of COVID-19 patients and …
Discovering key transcriptomic regulators in pancreatic ductal adenocarcinoma using Dirichlet process Gaussian mixture model
Abstract Pancreatic Ductal Adenocarcinoma (PDAC) is the most lethal type of pancreatic
cancer, late detection leading to its therapeutic failure. This study aims to determine the key …
cancer, late detection leading to its therapeutic failure. This study aims to determine the key …