Background There is lots of evidence that maternal peri-gestational metabolic, genomic and
environmental conditions are closely linked to metabolic and cardiovascular outcomes in …

Delaying pregnancy, which is on the rise, may increase the risk of cardiovascular disease in
both women and their children. The physiological mechanisms that lead to these effects are …

Advanced maternal age is associated with an increased risk of pregnancy complications. It
programmes sex-specific cardiovascular dysfunction in rat offspring, however the …

Advanced maternal age (≥ 35 years) is associated with pregnancy complications. Aging
impairs vascular reactivity and increases vascular stiffness. We hypothesized that uterine …

Assisted reproductive technology (ART) has rapidly developed and is now widely practised
worldwide. Both the characteristics of ART (handling gametes/embryos in vitro) and the …

Prenatal maternal stress is linked to adverse pregnancy and infant outcomes, including
shortened gestation lengths, low birth weights, cardio-metabolic dysfunction, and cognitive …

Background Frozen embryo transfer (FET) has become a widely employed assisted
reproductive technology technique. There have historically been concerns regarding the …

Maternal obesity predisposes offspring (F1) to cardiovascular disease. To evaluate basal
heart function and ischemia-reperfusion (IR) responses in F1 males and females of obese …

Advanced maternal age (≥ 35 years) increases the risk of vascular complications in
pregnancy that can result in fetal growth restriction and preeclampsia. Endoplasmic …

Research utilizing animals depends on the generation of offspring for use in experiments or
for the maintenance of animal colonies. While not considered by all, several different factors …