Electrical stimulation (EStim) has been shown to promote bone healing and regeneration
both in animal experiments and clinical treatments. Therefore, incorporating EStim into …

Non-union of bone following fracture is an orthopaedic condition with a high morbidity and
clinical burden. Despite its estimated global prevalence of nine million annually, the limit of …

Osteoporosis is a systemic metabolic bone disorder characterized by a decrease in bone
mass and degradation of the bone microstructure, leaving bones that are fragile and prone …

Mesenchymal stem cells (MSCs) are the main cell players in tissue repair and thanks to their
self-renewal and multi-lineage differentiation capabilities, they gained significant attention …

The electromagnetic field (EMF) has a great impact on our body. It has been successfully
used in physiotherapy for the treatment of bone disorders and osteoarthritis, as well as for …

Pulsed electromagnetic field (PEMF) stimulation, as a prospective, noninvasive, and safe
physical therapy strategy to accelerate bone repair has received tremendous attention in …

Bone fractures are one of the most commonly occurring injuries of the musculoskeletal
system. A highly complex physiological process, fracture healing has been studied …

Rapid and effective osseointegration is a great challenge in clinical practice. Endogenous
electronegative potentials spontaneously appear on bone defect sites and mediate healing …

The US FDA has approved pulsed electromagnetic fields (PEMFs) as a safe and effective
treatment for nonunions of bone. Despite its clinical use, the mechanisms of action of …

Impaired apoptosis is one of the hallmarks of cancer, and almost all of the non‐surgical
approaches of eradicating tumour cells somehow promote induction of apoptosis. Indeed …