Pro-inflammatory cytokines: The link between obesity and osteoarthritis

T Wang, C He - Cytokine & growth factor reviews, 2018 - Elsevier
Osteoarthritis (OA), characterized by joint malfunction and chronic disability, is the most
common form of arthritis. Clinical and animal experiments reveal that age-related OA is …

Risk of metabolic abnormalities in osteoarthritis: a new perspective to understand its pathological mechanisms

G Wei, K Lu, M Umar, Z Zhu, WW Lu, JR Speakman… - Bone Research, 2023 - nature.com
Although aging has traditionally been viewed as the most important risk factor for
osteoarthritis (OA), an increasing amount of epidemiological evidence has highlighted the …

Metabolic syndrome meets osteoarthritis

QI Zhuo, W Yang, J Chen, Y Wang - Nature Reviews Rheumatology, 2012 - nature.com
Metabolic osteoarthritis (OA) has now been characterized as a subtype of OA, and links
have been discovered between this phenotype and metabolic syndrome (MetS)—both with …

Adipokines: linking metabolic syndrome, the immune system, and arthritic diseases

V Francisco, C Ruiz-Fernández, J Pino, A Mera… - Biochemical …, 2019 - Elsevier
Metabolic syndrome (MetS) represents a cluster of metabolic and cardiovascular
complications, including obesity and visceral adiposity, insulin resistance, dyslipidemia …

What's new in our understanding of the role of adipokines in rheumatic diseases?

R Gómez, J Conde, M Scotece… - Nature Reviews …, 2011 - nature.com
Important advances in our understanding of the relationships between adipokines,
inflammation and the immune response have been achieved in the past 10 years. White …

Adipokine contribution to the pathogenesis of osteoarthritis

D Azamar-Llamas, G Hernandez-Molina… - Mediators of …, 2017 - Wiley Online Library
Recent studies have shown that overweight and obesity play an important role in the
development of osteoarthritis (OA). However, joint overload is not the only risk factor in this …

Biomechanics, obesity, and osteoarthritis. The role of adipokines: When the levee breaks

V Francisco, T Pérez, J Pino, V López… - Journal of …, 2018 - Wiley Online Library
Osteoarthritis is a high‐incidence painful and debilitating disease characterized by
progressive degeneration of articular joints, which indicates a breakdown in joint …

The role of adipokines in the pathogenesis of psoriasis

K Kiełbowski, E Bakinowska, P Ostrowski… - International Journal of …, 2023 - mdpi.com
Psoriasis is a chronic and immune-mediated skin condition characterized by pro-
inflammatory cytokines and keratinocyte hyperproliferation. Dendritic cells, T lymphocytes …

Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen …

A Koskinen, S Juslin, R Nieminen, T Moilanen… - Arthritis research & …, 2011 - Springer
Introduction Adiponectin is an adipokine that regulates energy metabolism and insulin
sensitivity, but recent studies have pointed also to a role in inflammation and arthritis. The …

[HTML][HTML] Adipokines: Biomarkers for osteoarthritis?

T Poonpet, S Honsawek - World journal of orthopedics, 2014 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is one of the most common degenerative joint diseases in aging
population. Obesity is an important risk factor for initiation and progression of OA. It is …