Malaria is a serious disease and was responsible for 429,000 deaths in 2015. Acute lung
injury/acute respiratory distress syndrome (ALI/ARDS) is one of the main clinical …

Malaria remains one of the greatest burdens to global health, causing nearly 500,000
deaths in 2014. When manifesting in the lungs, severe malaria causes acute lung …

Malaria-associated acute respiratory distress syndrome (MA-ARDS) is increasingly gaining
recognition as a severe malaria complication because of poor prognostic outcomes, high …

The DNA-binding protein high mobility group box-1 (HMGB-1) mediates proinflammatory
cytokines that contribute to acute lung injury (ALI). Although ALI is a frequent complication of …

Malaria is a serious disease, caused by the parasite of the genus Plasmodium, which was
responsible for 440,000 deaths in 2015. Acute lung injury/acute respiratory distress …

Malaria is an enormous burden on global health that caused 409,000 deaths in 2019.
Severe malaria can manifest in the lungs, an illness known as acute respiratory distress …

Background Malaria-associated acute respiratory distress syndrome (MA-ARDS) is a
potentially lethal complication of clinical malaria. Acute lung injury in MA-ARDS shares …

This study aimed to investigate the expression of sphingosine kinase 1 (SphK-1) and
sphingosine 1-phosphate receptor 3 (S1PR-3) in a mouse model of malaria-associated …

Malaria is the most important parasitic disease worldwide, accounting for 1 million deaths
each year. Severe malaria is a systemic illness characterized by dysfunction of brain tissue …

Background: The available evidence suggests that simvastatin plays a beneficial role in lung
injury. In addition, statins have been shown to inhibit the activity of inducible nitric oxide …