The extracellular promastigote stage of Leishmania spp. is transmitted to mammals by a
sand fly vector. Leishmania promastigotes ligate host macrophage receptors, triggering …

Leishmaniasis is a group of disease caused by the intracellular protozoan parasite of the
genus Leishmania. Infection by different species of Leishmania results in various host …

The Leishmania parasite is a widespread disease threat in tropical areas, causing
symptoms ranging from skin lesions to death. Leishmania parasites typically invade …

Major surface protease (MSP or GP63) is the most abundant glycoprotein localized to the
plasma membrane of Leishmania promastigotes. MSP plays several important roles in the …

Leishmania spp., the causative agents of leishmaniasis, are intracellular parasites,
transmitted to humans via the bite of their sand fly vectors. Once inoculated, the …

Parasitic protozoa are among the most important pathogens worldwide. Diseases such as
malaria, leishmaniasis, amoebiasis, giardiasis, trichomoniasis, and trypanosomiasis affect …

Leishmaniasis is a neglected parasitic disease for which the current antileishmania
therapeutics are hampered by drug toxicity, high cost, need for parenteral administration …

Evasion or subversion of host immune responses is a well-established paradigm in infection
with visceralizing leishmania. In this review, we summarize current findings supporting a …

Extracellular proteins secreted/released by protozoan parasites are key mediators of the
host–parasite interaction. To characterise the profile of proteins secreted/released by …

Background Protozoan parasites, such as Leishmania, still pose an enormous public health
problem in many countries throughout the world. Current measures are outdated and have …