Pathophysiology of myocardial infarction

A Skyschally, R Schulz, G Heusch - Herz, 2008 - search.proquest.com
One or several short cycles of ischemia/reperfusion before (preconditioning) or after
(postconditioning) a sustained coronary occlusion with subsequent reperfusion reduce the …

Ischemic preconditioning: protection against myocardial necrosis and apoptosis

EK Iliodromitis, A Lazou… - Vascular health and risk …, 2007 - Taylor & Francis
The phenomenon of ischemic preconditioning has been recognized as one of the most
potent mechanisms to protect against myocardial ischemic injury. In experimental animals …

Tanshinone IIA inhibits miR-1 expression through p38 MAPK signal pathway in post-infarction rat cardiomyocytes

Y Zhang, L Zhang, W Chu, B Wang, J Zhang… - Cellular Physiology and …, 2011 - karger.com
Tanshinone IIA is a fat-soluble pharmacologically active ingredient of Danshen, a well-
known traditional Chinese medicine used for cardiovascular diseases such as coronary …

Nitroglycerine limits infarct size through S-nitrosation of cyclophilin D: a novel mechanism for an old drug

SI Bibli, A Papapetropoulos… - Cardiovascular …, 2019 - academic.oup.com
Aims Nitroglycerine (NTG) given prior to an ischaemic insult exerts cardioprotective effects.
However, whether administration of an acute low dose of NTG in a clinically relevant manner …

ALDH2 gene polymorphism in different types of cancers and its clinical significance

R Li, Z Zhao, M Sun, J Luo, Y Xiao - Life sciences, 2016 - Elsevier
Abstract Aldehyde dehydrogenase 2 (ALDH2), an important mitochondrial enzyme
governing ethanol metabolism, displays polymorphism in human. Recent evidence …

Activation of ALDH2 with low concentration of ethanol attenuates myocardial ischemia/reperfusion injury in diabetes rat model

PF Kang, WJ Wu, Y Tang, L Xuan… - Oxidative Medicine …, 2016 - Wiley Online Library
The aim of this paper is to observe the change of mitochondrial aldehyde dehydrogenase 2
(ALDH2) when diabetes mellitus (DM) rat heart was subjected to ischemia/reperfusion (I/R) …

Protein S-nitrosylation in preconditioning and postconditioning

C Penna, C Angotti, P Pagliaro - Experimental Biology and …, 2014 - journals.sagepub.com
The coronary artery disease is a leading cause of death and morbidity worldwide. This
disease has a complex pathophysiology that includes multiple mechanisms. Among these is …

Activation of extracellular signal-regulated kinases during dehydration in the African clawed frog, Xenopus laevis

AI Malik, KB Storey - Journal of Experimental Biology, 2009 - journals.biologists.com
In its native environment the African clawed frog, Xenopus laevis, can experience
seasonally arid conditions that impose dehydration stress. Activation of intracellular signal …

Pharmacological pre-and post-conditioning agents: reperfusion-injury of the heart revisited

I Andreadou, EK Iliodromitis, M Koufaki… - Mini reviews in …, 2008 - ingentaconnect.com
Ischemic preconditioning (PC) and postconditioning (PostC) are endogenous mechanisms
of protection of the ischemic heart. In brief, short cycles of sublethal ischemia separated by …

Exercise-induced late preconditioning in mice is triggered by eNOS-dependent generation of nitric oxide and activation of PKCε and is mediated by increased iNOS …

Y Guo, Q Li, YT Xuan, WJ Wu, W Tan, J Slezak… - International journal of …, 2021 - Elsevier
The purpose of this study was to assess whether short-term, mild exercise induces
protection against myocardial infarction and, if so, what role the eNOS-PKCε-iNOS axis …