Steroid hormone receptors are ligand-binding transcription factors essential for mammalian
physiology. The androgen receptor (AR) binds androgens mediating gene expression for …

The androgen receptor (AR) is a member of the ligand-activated nuclear receptor family of
transcription factors. AR's transactivation activity is turned on by the binding of androgens …

Androgen insensitivity describes the inability of cells to respond adequately to androgens.
The clinical aspects are well characterized and described in the androgen insensitivity …

External genitalia are prominent organs showing hormone-dependent sexual differentiation.
Androgen is an essential regulator of masculinization of the genital tubercle, which is the …

Sulfide-quinone oxidoreductase (SQR) is a key enzyme of sulfide metabolism in metazoans,
and responsible for oxidizing sulfide into thiosulfate and transmitting the generated electrons …

The formation of the external genitalia is a highly complex developmental process,
considering it involves a wide range of cell types and results in sexually dimorphic …

Copy number variations (CNVs) are important forms of structural variation in human and
animals and can be considered as a major genetic component of phenotypic diversity. Here …

Die Wahrnehmung von Geschlecht erfährt zurzeit eine dramatische Änderung sowohl in der
Biologie als auch in Medizin und Gesellschaft. Die Erkenntnisse der Genetik und der …

Steroid hormone receptors are ligand-binding transcription factors essential for mammalian
physiology. The androgen receptor (AR) binds androgens mediating gene expression for …

Auch außerhalb des Genitales kommt es zu geschlechtsspezifischen Entwicklungen. Eines
der wichtigsten Beispiele ist das menschliche Gehirn, wobei Assoziationen …